{"id":1350,"date":"2026-06-21T15:32:01","date_gmt":"2026-06-21T14:32:01","guid":{"rendered":"http:\/\/seamlessbio.de\/?page_id=1350"},"modified":"2026-09-26T22:01:05","modified_gmt":"2026-09-26T21:01:05","slug":"human-serum-otc","status":"publish","type":"page","link":"https:\/\/seamlessbio.de\/de\/human-serum-otc\/","title":{"rendered":"Humanes Serum OTC (gemischt)"},"content":{"rendered":"\t\t
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\n Home<\/a>\n \/<\/span>\n Human Serum<\/a>\n \/<\/span>\n Human Serum OTC<\/strong>\n <\/div>\n\n \n
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\n SeamlessBio \u2014 Human Serum<\/span>\n

Human Serum OTC<\/h1>\n

\n EU and US-origin off-the-clot human serum from mixed donors \u2014 capturing\n the full native growth factor spectrum released by platelet degranulation,\n including PDGF, EGF, TGF-\u03b2 and IGF-1, for cell expansion, primary cell\n culture and process development without blood-type or gender restrictions.\n <\/p>\n

\n Request a Quote<\/a>\n View in Shop<\/a>\n Request a Sample<\/a>\n <\/div>\n <\/div>\n <\/div>\n\n \n
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\n 01<\/span>\n

Native Growth Factor Profile<\/h3>\n

\n Collected during platelet degranulation \u2014 retains the full physiological\n complement of PDGF, EGF, TGF-\u03b2 and IGF-1 that standard clotted serum\n loses in processing.\n <\/p>\n <\/div>\n\n

\n 02<\/span>\n

No Blood-Type Restriction<\/h3>\n

\n Mixed-donor pool with no blood-type or gender selection \u2014 the most cost-effective\n OTC serum format for applications that do not require defined donor profiles.\n <\/p>\n <\/div>\n\n

\n 03<\/span>\n

EU & US Certified Origin<\/h3>\n

\n Sourced from certified EU and\/or US donor centres. ATMP-relevant documentation\n (Ph. Eur. 5.2.12) available on request for advanced therapy process development.\n <\/p>\n <\/div>\n\n

\n 04<\/span>\n

Flexible Specification<\/h3>\n

\n Available as standard OTC or on request as heat inactivated, gamma irradiated\n or low-endotoxin. Donor age specification, bulk volumes and lot reservation\n available.\n <\/p>\n <\/div>\n\n <\/div>\n\n \n

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The growth-factor-rich human serum for cell expansion<\/h2>\n

\n Off-the-clot (OTC) serum is collected during the clotting process rather than\n after centrifugation of fully clotted blood. This timing captures the platelet\n degranulation event \u2014 releasing PDGF, EGF, TGF-\u03b2 and IGF-1 in their native\n concentrations \u2014 giving OTC serum a substantially richer growth factor profile\n than standard clotted human serum.\n <\/p>\n

\n This makes Human Serum OTC the preferred choice for cell expansion applications\n requiring human serum growth factor support: mesenchymal stem cell (MSC)\n expansion, primary fibroblast culture, general cell expansion for process\n development and research-scale applications where the endogenous growth factor\n background directly influences cell behaviour.\n <\/p>\n

\n SeamlessBio Human Serum OTC is sourced from certified EU and US donor centres\n with no blood-type or gender selection \u2014 providing maximum pool size and\n consistent average growth factor levels. Where blood type or donor gender\n must be defined, our Human Serum OTC Type AB Male offers the same OTC\n collection format with stricter donor controls.\n <\/p>\n <\/div>\n\n

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Typical applications<\/h3>\n