{"id":2122,"date":"2026-06-28T20:55:09","date_gmt":"2026-06-28T19:55:09","guid":{"rendered":"http:\/\/seamlessbio.de\/?page_id=2122"},"modified":"2026-06-28T20:59:12","modified_gmt":"2026-06-28T19:59:12","slug":"calf-serum-cs","status":"publish","type":"page","link":"https:\/\/seamlessbio.de\/de\/calf-serum-cs\/","title":{"rendered":"K\u00e4lberserum"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"2122\" class=\"elementor elementor-2122\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-dcef0aa e-con e-atomic-element e-flexbox-base e-2110e57 \" data-id=\"dcef0aa\" data-element_type=\"e-flexbox\" data-e-type=\"e-flexbox\" data-interaction-id=\"dcef0aa\">\n    \t\t<div class=\"elementor-element elementor-element-63786c5 elementor-widget elementor-widget-html\" data-id=\"63786c5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<script type=\"application\/ld+json\">\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@graph\": [\n    {\n      \"@type\": \"BreadcrumbList\",\n      \"itemListElement\": [\n        { \"@type\": \"ListItem\", \"position\": 1, \"name\": \"Home\", \"item\": \"https:\/\/www.seamlessbio.de\/\" }\n        { \"@type\": \"ListItem\", \"position\": 2, \"name\": \"Products\", \"item\": \"https:\/\/www.seamlessbio.de\/products\/other-animal-sera\/\" }\n        { \"@type\": \"ListItem\", \"position\": 3, \"name\": \"Calf Serum (CS \/ BCS)\", \"item\": \"https:\/\/www.seamlessbio.de\/products\/other-animal-sera\/calf-serum-cs\/\" }\n      ]\n    },\n    {\n      \"@type\": \"Product\",\n      \"name\": \"Calf Serum (CS \/ BCS)\",\n      \"brand\": { \"@type\": \"Brand\", \"name\": \"SeamlessBio\" },\n      \"description\": \"Bovine Calf Serum from calves 14 days to 6 months. The most cost-effective bovine serum option \u2014 40\u201360% lower cost than FBS. EU, US and Australian origin.\",\n      \"offers\": {\n        \"@type\": \"Offer\",\n        \"url\": \"https:\/\/www.seamlessbio.de\/products\/other-animal-sera\/calf-serum-cs\/\",\n        \"availability\": \"https:\/\/schema.org\/InStock\",\n        \"priceCurrency\": \"EUR\"\n      }\n    },\n    {\n      \"@type\": \"FAQPage\",\n      \"mainEntity\": [\n        {\n          \"@type\": \"Question\",\n          \"name\": \"What is the difference between Calf Serum and Newborn Calf Serum?\",\n          \"acceptedAnswer\": { \"@type\": \"Answer\", \"text\": \"NCS comes from calves \u226410 days old with lower IgG and slightly higher growth factor content. Calf Serum comes from calves up to 6 months with progressively higher IgG. For routine immortalised cell lines both perform equivalently \u2014 Calf Serum is the more economical choice.\" }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Can Calf Serum replace FBS in all applications?\",\n          \"acceptedAnswer\": { \"@type\": \"Answer\", \"text\": \"For standard immortalised cell lines, vaccine production and veterinary research \u2014 yes. For hybridoma, sensitive primary cells and ATMP manufacturing where ultra-low IgG is required, FBS remains preferred.\" }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Is Australian origin Calf Serum available?\",\n          \"acceptedAnswer\": { \"@type\": \"Answer\", \"text\": \"Yes \u2014 EU, US and Australian origin are all available. Australian origin provides the highest biosafety documentation and is accepted for USDA and EU regulatory submissions.\" }\n        }\n      ]\n    }\n  ]\n}\n<\/script>\n<section class=\"sb-cs-page\">\n<div class=\"sb-cs-container\">\n  <nav class=\"sb-cs-bc\"><a href=\"https:\/\/www.seamlessbio.de\/\">Home<\/a><span>\/<\/span><a href=\"https:\/\/www.seamlessbio.de\/products\/other-animal-sera\/\">Animal Sera<\/a><span>\/<\/span><strong>Calf Serum (CS)<\/strong><\/nav>\n  <div class=\"sb-cs-hero\">\n    <div class=\"sb-cs-hero-text\">\n      <span class=\"sb-cs-eyebrow\">Calves 14 Days \u2013 6 Months \u00b7 USA \u00b7 New Zealand \u00b7 Australian Origin \u00b7 Processed in Germany<\/span>\n      <h1>Calf Serum (CS \/ BCS)<\/h1>\n      <p>Calf Serum (CS), also known as Bovine Calf Serum (BCS), is collected from healthy bovine calves between 14 days and 6 months of age. The most cost-effective bovine serum option \u2014 40\u201360% lower cost than FBS \u2014 with excellent growth-promoting activity for robust cell lines and high-volume manufacturing applications.<\/p>\n      <div class=\"sb-cs-tags\"><span>CS \/ BCS<\/span><span>14 Days \u2013 6 Months<\/span><span>40\u201360% vs FBS Cost<\/span><span>USA \u00b7 New Zealand \u00b7 Australian<\/span><span>Vaccine Production<\/span><\/div>\n      <div class=\"sb-cs-btns\"><a href=\"https:\/\/www.seamlessbio.de\/about-us\/contact-imprint\/\" class=\"sb-cs-btn\">Request Quote \/ Sample<\/a><a href=\"https:\/\/shop.seamlessbio.de\" class=\"sb-cs-btn-o\">Order in Shop<\/a><\/div>\n    <\/div>\n  <\/div>\n  <div class=\"sb-cs-facts\">\n    <div class=\"sb-cs-fact\"><span class=\"sb-cs-fn\">14d \u2013 6mo<\/span><span>Donor age at collection<\/span><\/div>\n    <div class=\"sb-cs-fact\"><span class=\"sb-cs-fn\">40\u201360%<\/span><span>Lower cost vs FBS \u2014 same concentration direct replacement<\/span><\/div>\n    <div class=\"sb-cs-fact\"><span class=\"sb-cs-fn\">High<\/span><span>Growth factor content \u2014 excellent support for robust cell lines<\/span><\/div>\n    <div class=\"sb-cs-fact\"><span class=\"sb-cs-fn\">EU \u00b7 US \u00b7 AUS<\/span><span>Multiple origins \u2014 BSE\/TSE documentation per origin<\/span><\/div>\n  <\/div>\n  <div class=\"sb-cs-section\">\n    <h2>Applications<\/h2>\n    <div class=\"sb-cs-app-grid\">\n      <div class=\"sb-cs-app\"><h3>Large-Scale Routine Cell Line Maintenance<\/h3><p>Most economical option for high-volume culture of CHO, HeLa, Vero, HEK293, 3T3, BHK-21 and MDCK. Direct FBS replacement at the same concentration \u2014 40\u201360% cost saving with equivalent performance for robust cell lines.<\/p><\/div>\n      <div class=\"sb-cs-app\"><h3>Veterinary Vaccine Production<\/h3><p>Widely used in foot-and-mouth disease, veterinary virus vaccine and antigen production in BHK-21 and Vero cells. Cost efficiency is critical at large scale, making CS the standard choice for many established veterinary vaccine processes.<\/p><\/div>\n      <div class=\"sb-cs-app\"><h3>Agricultural & Veterinary Research<\/h3><p>Species-matched or cost-effective serum supplement for bovine, ovine and porcine primary cell lines in veterinary, agricultural and animal science research applications.<\/p><\/div>\n      <div class=\"sb-cs-app\"><h3>Large-Scale Cell Banking<\/h3><p>Most economical bovine serum for high-volume master and working cell bank cryopreservation where FBS cost represents a significant portion of total manufacturing cost.<\/p><\/div>\n      <div class=\"sb-cs-app\"><h3>Bioreactor Seed Train \u2014 Research Grade<\/h3><p>Cost optimisation at N-2 and N-1 seed train stages before switching to FBS or serum-free media at final production scale. Reduces per-litre serum cost during scale-up expansion phases.<\/p><\/div>\n      <div class=\"sb-cs-app\"><h3>Cell-Based Assay Development<\/h3><p>Routine cytotoxicity, proliferation and metabolic assays where IgG background level is not critical for the assay readout \u2014 and where throughput drives cost considerations.<\/p><\/div>\n    <\/div>\n  <\/div>\n  <div class=\"sb-cs-section sb-cs-alt\">\n    <h2>Product Information<\/h2>\n    <table class=\"sb-cs-info\">\n      <tr><td>Product type<\/td><td>Calf Serum (CS \/ BCS \u2014 Bovine Calf Serum)<\/td><\/tr>\n      <tr><td>Donor age<\/td><td>14 days to 6 months<\/td><\/tr>\n      <tr><td>IgG content<\/td><td>Medium \u2014 increasing progressively with calf age<\/td><\/tr>\n      <tr><td>Collection<\/td><td>Pooled healthy calves, sterile bleed<\/td><\/tr>\n      <tr><td>Filtration<\/td><td>0.2 \u00b5m sterile filtered<\/td><\/tr>\n      <tr><td>Endotoxin<\/td><td>Tested per lot \u2014 LAL method<\/td><\/tr>\n      <tr><td>Haemoglobin<\/td><td>\u226420 mg\/dL<\/td><\/tr>\n      <tr><td>Mycoplasma<\/td><td>Tested \u2014 negative<\/td><\/tr>\n      <tr><td>BVDV<\/td><td>Tested \u2014 negative<\/td><\/tr>\n      <tr><td>Origin<\/td><td>USA, New Zealand or Australian \u2014 specify on order<\/td><\/tr>\n      <tr><td>Processing location<\/td><td>Germany (Passau) \u2014 processed in-house by SeamlessBio<\/td><\/tr>\n      <tr><td>Processing options<\/td><td>Standard \u00b7 Heat Inactivated (56\u00b0C\/30 min) \u00b7 Gamma Irradiated on request<\/td><\/tr>\n      <tr><td>Volumes<\/td><td>100 mL, 500 mL \u00b7 Bulk on request<\/td><\/tr>\n      <tr><td>Storage<\/td><td>\u221220\u00b0C \u00b7 Batch reservation available<\/td><\/tr>\n      <tr><td>Documentation<\/td><td>CoA, CoO, MSDS, TSE\/BSE Statement<\/td><\/tr>\n      <tr><td>Regulatory status<\/td><td>For research use only<\/td><\/tr>\n    <\/table>\n  <\/div>\n  <div class=\"sb-cs-section\">\n    <h2>Frequently Asked Questions<\/h2>\n    <div class=\"sb-cs-faqs\">\n      <div class=\"sb-cs-faq\"><h3>What is the difference between Calf Serum and Newborn Calf Serum?<\/h3><p>Newborn Calf Serum (NCS) comes from calves \u226410 days old with lower IgG and slightly higher growth factor content \u2014 closer to FBS in profile. Calf Serum comes from calves up to 6 months old with progressively higher IgG. For most routine immortalised cell line applications both are equivalent in performance \u2014 CS is the more economical choice.<\/p><\/div>\n      <div class=\"sb-cs-faq\"><h3>Can Calf Serum replace FBS in all applications?<\/h3><p>For standard immortalised cell lines, high-volume vaccine production and veterinary research \u2014 yes. For hybridoma culture, sensitive primary cells, iPSC culture or ATMP manufacturing where ultra-low IgG and maximum growth factor content are critical, FBS remains the better choice.<\/p><\/div>\n      <div class=\"sb-cs-faq\"><h3>Is Australian origin Calf Serum available?<\/h3><p>Yes \u2014 Australian, US and EU origin are available. Australian origin provides the highest biosafety documentation (negligible BSE\/TSE risk per OIE classification) and is accepted for USDA and EU regulatory submissions. Specify your required origin at the time of enquiry.<\/p><\/div>\n    <\/div>\n  <\/div>\n  <div class=\"sb-cs-section sb-cs-alt\">\n    <h2>Related Products<\/h2>\n    <div class=\"sb-cs-related\">\n      <a href=\"https:\/\/www.seamlessbio.de\/products\/other-animal-sera\/newborn-calf-serum-ncs\/\" class=\"sb-cs-rel\"><h3>Newborn Calf Serum (NCS)<\/h3><p>Calves \u226410 days \u2014 lower IgG, higher growth factor profile.<\/p><\/a>\n      <a href=\"https:\/\/www.seamlessbio.de\/products\/fetal-bovine-serum\/\" class=\"sb-cs-rel\"><h3>Fetal Bovine Serum (FBS)<\/h3><p>9 grades \u2014 for sensitive applications requiring maximum growth factor content.<\/p><\/a>\n      <a href=\"https:\/\/www.seamlessbio.de\/products\/other-animal-sera\/bovine-products\/\" class=\"sb-cs-rel\"><h3>Bovine Products Hub<\/h3><p>All bovine products \u2014 FBS, NCS, CS and BSA overview.<\/p><\/a>\n      <a href=\"https:\/\/www.seamlessbio.de\/applications\/vaccine-production\/\" class=\"sb-cs-rel\"><h3>Vaccine Production Guide<\/h3><p>CS and NCS in Vero, MDCK and BHK-21 vaccine workflows.<\/p><\/a>\n    <\/div>\n  <\/div>\n  <div class=\"sb-cs-cta\">\n    <h2>Request Calf Serum \u2014 Quote or Sample<\/h2>\n    <p>EU, US and Australian origin available. Heat inactivated on request. Batch reservation. Full documentation included.<\/p>\n    <div class=\"sb-cs-cta-btns\"><a href=\"https:\/\/www.seamlessbio.de\/about-us\/contact-imprint\/\" class=\"sb-cs-btn-w\">Contact Us<\/a><a href=\"mailto:info@seamlessbio.de?subject=Calf%20Serum%20CS%20Quote\" class=\"sb-cs-btn-oo\">info@seamlessbio.de<\/a><\/div>\n    <p class=\"sb-cs-ruo\">For research use only.<\/p>\n  <\/div>\n<\/div>\n<\/section>\n<style>\n.sb-cs-page,.sb-cs-page *,.sb-cs-page *::before,.sb-cs-page *::after{box-sizing:border-box}\n.sb-cs-page{font-family:Arial,sans-serif;color:#1a1a1a;background:#fff;padding:60px 32px 90px}\n.sb-cs-container{max-width:1200px;margin:0 auto}\n.sb-cs-bc{display:flex;flex-wrap:wrap;gap:6px;align-items:center;font-size:13px;color:#888;margin-bottom:28px}\n.sb-cs-bc a{color:#18b7b2!important;text-decoration:none!important;font-weight:600}.sb-cs-bc strong{color:#111}.sb-cs-bc span{color:#ccc}\n.sb-cs-hero{background:linear-gradient(135deg,#0d9490 0%,#18b7b2 60%,#1ec8c2 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18px}}\n<\/style>\t\t\t\t<\/div>\n\t\t\n<\/div>\n\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Home\/Animal Sera\/Calf Serum (CS) Calves 14 Days \u2013 6 Months \u00b7 USA \u00b7 New Zealand \u00b7 Australian Origin \u00b7 Processed in Germany Calf Serum (CS \/ BCS) Calf Serum (CS), [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_eb_attr":"","footnotes":""},"class_list":["post-2122","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.0 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Calf Serum (CS \/ BCS) | Most Economical Bovine Serum | SeamlessBio<\/title>\n<meta name=\"description\" content=\"Calf Serum (CS\/BCS) 14d\u20136mo \u2014 40\u201360% vs FBS. 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