{"id":2412,"date":"2026-07-10T14:46:51","date_gmt":"2026-07-10T13:46:51","guid":{"rendered":"https:\/\/seamlessbio.de\/?page_id=2412"},"modified":"2026-07-10T14:48:43","modified_gmt":"2026-07-10T13:48:43","slug":"human-plasma-type-ab-male","status":"publish","type":"page","link":"https:\/\/seamlessbio.de\/de\/human-plasma-type-ab-male\/","title":{"rendered":"Menschliches Plasma \u2013 Typ AB, m\u00e4nnlich"},"content":{"rendered":"<div data-elementor-type=\"wp-page\" data-elementor-id=\"2412\" class=\"elementor elementor-2412\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a9bd7f8 e-con e-atomic-element e-flexbox-base e-6965ff0\" data-id=\"a9bd7f8\" data-element_type=\"e-flexbox\" data-e-type=\"e-flexbox\" data-interaction-id=\"a9bd7f8\">\n    \t\t<div class=\"elementor-element elementor-element-77281ef elementor-widget elementor-widget-html\" data-id=\"77281ef\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<!-- ============================================================\n  SEAMLESSBIO WORDPRESS \u2014 ELEMENTOR HTML WIDGET\n  PAGE: Human Plasma \u2014 Type AB Male\n  URL SLUG: \/human-plasma-type-ab-male\/\n\n  YOAST SEO:\n  SEO Title:       Human Plasma Type AB Male | EU & US Origin | CAR-T & Cell Therapy | SeamlessBio\n  Slug:            human-plasma-type-ab-male\n  Focus Keyword:   human plasma type AB male\n  Meta Description: Human plasma from male AB blood-type donors \u2014 no anti-A or anti-B antibodies. For CAR-T expansion, ATMP manufacturing and immunologically sensitive cell culture. EU & US origin, full viral screening, batch reservation. SeamlessBio.\n  Image Filename:  human-plasma-type-ab-male-flasche.png\n============================================================ -->\n\n<style>\n*, *::before, *::after { box-sizing: border-box; }\n.sb-pab { font-family: -apple-system, BlinkMacSystemFont, \"Segoe UI\", Arial, sans-serif; font-size: 16px; color: #1a2e35; line-height: 1.65; max-width: 1100px; margin: 0 auto; }\n.sb-pab-bc { font-size: 14px; color: #888; margin-bottom: 24px; }\n.sb-pab-bc a { color: #18b7b2; text-decoration: none; }\n.sb-pab-hero { background: linear-gradient(135deg, #18b7b2 0%, #a8e6e4 60%, #e8f9f8 100%); border-radius: 20px; padding: 56px 48px; display: grid; grid-template-columns: 1fr 340px; gap: 40px; align-items: center; margin-bottom: 48px; min-height: 300px; }\n.sb-pab-eyebrow { font-size: 12px; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: rgba(255,255,255,0.85); margin-bottom: 14px; }\n.sb-pab-hero h1 { font-size: 40px; font-weight: 800; color: #fff; margin: 0 0 16px 0; 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background: #18b7b2; color: #fff; text-decoration: none; font-size: 13px; font-weight: 700; letter-spacing: 0.06em; text-transform: uppercase; padding: 16px 36px; border-radius: 50px; }\n@media (max-width: 900px) {\n  .sb-pab-hero { grid-template-columns: 1fr; padding: 36px 28px; }\n  .sb-pab-hero-img { display: none; }\n  .sb-pab-hero h1 { font-size: 30px; }\n  .sb-pab-usps { grid-template-columns: repeat(2, 1fr); }\n  .sb-pab-twocol { grid-template-columns: 1fr; gap: 32px; }\n  .sb-pab-qs-grid { grid-template-columns: repeat(2, 1fr); }\n}\n@media (max-width: 480px) {\n  .sb-pab-hero { padding: 28px 20px; }\n  .sb-pab-hero h1 { font-size: 26px; }\n  .sb-pab-usps { grid-template-columns: 1fr; }\n  .sb-pab-qs-grid { grid-template-columns: 1fr; }\n  .sb-pab-cta { padding: 36px 20px; }\n  .sb-pab-table { font-size: 13px; }\n  .sb-pab-table td, .sb-pab-table th { padding: 10px 12px; }\n  .sb-pab-compare { font-size: 12px; }\n}\n<\/style>\n\n<div class=\"sb-pab\">\n\n  <div class=\"sb-pab-bc\">\n    <a href=\"https:\/\/seamlessbio.de\/de\/\">Startseite<\/a> \/\n    <a href=\"https:\/\/seamlessbio.de\/de\/seren-und-plasma\/\">Seren &amp; Plasma<\/a> \/\n    <a href=\"https:\/\/seamlessbio.de\/de\/plasma-aus-der-menschlichen-apherese\/\">Humanplasma<\/a> \/\n    <strong>Human Plasma Type AB Male<\/strong>\n  <\/div>\n\n  <div class=\"sb-pab-hero\">\n    <div>\n      <div class=\"sb-pab-eyebrow\">SeamlessBio \u2014 Human Plasma<\/div>\n      <h1>Human Plasma \u2014 Type AB, Male Donors<\/h1>\n      <p class=\"sb-pab-hero-desc\">Plasma from certified male AB blood-type donors \u2014 free of anti-A and anti-B antibodies. The preferred plasma format for CAR-T expansion, NK cell manufacturing, MSC culture and any immunologically sensitive cell therapy application. EU and US origin, with batch reservation for ATMP programmes.<\/p>\n      <div class=\"sb-pab-btns\">\n        <a class=\"sb-pab-btn-dark\" href=\"mailto:info@seamlessbio.de?subject=Human%20Plasma%20Type%20AB%20Male\">Informationen anfordern<\/a>\n        <a class=\"sb-pab-btn-outline\" href=\"https:\/\/shop.seamlessbio.de\/collections\/humanserum-plasma-und-mehr\">Im Shop ansehen<\/a>\n      <\/div>\n    <\/div>\n    <div class=\"sb-pab-hero-img\">\n      <img decoding=\"async\" src=\"https:\/\/www.seamlessbio.de\/uploads\/human-plasma-type-ab-male-flasche.png\" alt=\"Human Plasma Type AB Male \u2014 SeamlessBio\" onerror=\"this.parentElement.innerHTML='Product image placeholder'\">\n    <\/div>\n  <\/div>\n\n  <div class=\"sb-pab-qs\">\n    <h2>Related products \u2014 find the right format<\/h2>\n    <div class=\"sb-pab-qs-grid\">\n      <a class=\"sb-pab-qs-card\" href=\"https:\/\/seamlessbio.de\/de\/human-serum-otc-type-ab-male\/\">\n        <div class=\"sb-pab-qs-label\">Cell culture, no coagulation factors, max growth factors<\/div>\n        <div class=\"sb-pab-qs-link\">Menschliches Serum, OTC, Typ AB, m\u00e4nnlich \u2192<\/div>\n      <\/a>\n      <a class=\"sb-pab-qs-card\" href=\"https:\/\/seamlessbio.de\/de\/human-plasma-pooled\/\">\n        <div class=\"sb-pab-qs-label\">IVD calibrators, large-scale assay matrix<\/div>\n        <div class=\"sb-pab-qs-link\">Human Plasma Pooled \u2192<\/div>\n      <\/a>\n      <a class=\"sb-pab-qs-card\" href=\"https:\/\/seamlessbio.de\/de\/menschliches-thrombozytenlysat\/\">\n        <div class=\"sb-pab-qs-label\">Xeno-free MSC expansion, FBS alternative<\/div>\n        <div class=\"sb-pab-qs-link\">Lysat aus menschlichen Blutpl\u00e4ttchen (hPL) \u2192<\/div>\n      <\/a>\n      <a class=\"sb-pab-qs-card\" href=\"https:\/\/seamlessbio.de\/de\/human-plasma-single-donor\/\">\n        <div class=\"sb-pab-qs-label\">Individual traceability, disease-state panels<\/div>\n        <div class=\"sb-pab-qs-link\">Human Plasma Single Donor \u2192<\/div>\n      <\/a>\n      <a class=\"sb-pab-qs-card\" href=\"https:\/\/seamlessbio.de\/de\/human-serum-type-ab-male\/\">\n        <div class=\"sb-pab-qs-label\">Converted serum, Type AB male, sterile filtered<\/div>\n        <div class=\"sb-pab-qs-link\">Human Serum Type AB Male \u2192<\/div>\n      <\/a>\n      <a class=\"sb-pab-qs-card\" href=\"https:\/\/seamlessbio.de\/de\/plasma-aus-der-menschlichen-apherese\/\">\n        <div class=\"sb-pab-qs-label\">Full plasma portfolio including apheresis<\/div>\n        <div class=\"sb-pab-qs-link\">Human Plasma Overview \u2192<\/div>\n      <\/a>\n    <\/div>\n  <\/div>\n\n  <div class=\"sb-pab-usps\">\n    <div class=\"sb-pab-usp\">\n      <div class=\"sb-pab-usp-num\">01<\/div>\n      <h3>No Anti-A\/B Antibodies<\/h3>\n      <p>AB blood type confirmed \u2014 universally compatible with human cells of any ABO blood group. No alloantibody-mediated interference.<\/p>\n    <\/div>\n    <div class=\"sb-pab-usp\">\n      <div class=\"sb-pab-usp-num\">02<\/div>\n      <h3>Male Donors Only<\/h3>\n      <p>Reduced sex hormone variability lot-to-lot \u2014 stable oestrogen and progesterone background for hormone-sensitive protocols.<\/p>\n    <\/div>\n    <div class=\"sb-pab-usp\">\n      <div class=\"sb-pab-usp-num\">03<\/div>\n      <h3>Herkunft: EU und USA<\/h3>\n      <p>Certified donor centres in Europe and the United States \u2014 specify origin at order. Full IVDR and GMP-process documentation available.<\/p>\n    <\/div>\n    <div class=\"sb-pab-usp\">\n      <div class=\"sb-pab-usp-num\">04<\/div>\n      <h3>Sammelreservierung<\/h3>\n      <p>Lot reservation for ATMP programmes \u2014 no prepayment during evaluation. EU cold stock, call-off in partial deliveries as needed.<\/p>\n    <\/div>\n  <\/div>\n\n  <div class=\"sb-pab-twocol\">\n    <div>\n      <h2>Why AB blood type \u2014 and why male donors only?<\/h2>\n      <p>Blood group AB is the only group carrying neither anti-A nor anti-B antibodies. In all other blood groups \u2014 A, B and O \u2014 these alloantibodies circulate in plasma and can activate complement, lyse cells bearing the corresponding antigen, and create non-specific immune effects in culture systems that are difficult to distinguish from assay signal.<\/p>\n      <p>Restricting the donor pool to male donors addresses a second source of variability: sex hormone concentrations. Female plasma contains cyclically fluctuating oestrogens, progesterone and FSH\/LH \u2014 hormones that activate steroid receptors in cultured cells, alter proliferation rates and confound results in hormone-sensitive assays. Male donors provide a consistently low and stable sex hormone background.<\/p>\n      <p>Together, AB blood type and male-only donor selection give the lowest alloantibody background and most consistent hormonal environment available in non-processed human plasma \u2014 which is why AB male plasma is specified in CAR-T protocols and ATMP workflows where regulatory agencies increasingly scrutinise animal-derived component profiles.<\/p>\n      <p>See also: <a href=\"https:\/\/seamlessbio.de\/de\/human-serum-otc-type-ab-male\/\">Menschliches Serum, OTC, Typ AB, m\u00e4nnlich<\/a> \u2014 the serum equivalent, without coagulation factors, with higher growth factor release from platelet degranulation during clotting.<\/p>\n    <\/div>\n    <div>\n      <h3>Typische Anwendungsbereiche<\/h3>\n      <ul class=\"sb-pab-bullets\">\n        <li>CAR-T cell manufacturing \u2014 ex vivo T cell activation and expansion media supplement<\/li>\n        <li>NK cell expansion \u2014 allogeneic cell therapy programmes<\/li>\n        <li>MSC expansion in plasma-supplemented, xeno-free protocols<\/li>\n        <li>IVD calibrator manufacturing \u2014 universal AB matrix avoids alloantibody interference<\/li>\n        <li>Complement activity studies requiring AB background<\/li>\n        <li>Cell therapy process development requiring defined, consistent plasma supplement<\/li>\n        <li>Haematopoietic stem cell (HSC) culture and expansion<\/li>\n      <\/ul>\n    <\/div>\n  <\/div>\n\n  <h2 class=\"sb-pab-compare-title\">AB male plasma vs. other plasma formats<\/h2>\n  <table class=\"sb-pab-compare\">\n    <thead>\n      <tr>\n        <th>Parameter<\/th>\n        <th>AB Male Plasma<\/th>\n        <th>Mixed Blood Group Plasma<\/th>\n        <th>Mixed Gender Plasma<\/th>\n      <\/tr>\n    <\/thead>\n    <tbody>\n      <tr><td>Anti-A antibodies<\/td><td>Absent<\/td><td>Present (A\/O donors)<\/td><td>Variable<\/td><\/tr>\n      <tr><td>Anti-B antibodies<\/td><td>Absent<\/td><td>Present (B\/O donors)<\/td><td>Variable<\/td><\/tr>\n      <tr><td>Oestrogen \/ progesterone<\/td><td>Low, stable<\/td><td>Low, stable<\/td><td>Fluctuating<\/td><\/tr>\n      <tr><td>Inter-lot hormonal variability<\/td><td>Niedrig<\/td><td>Niedrig<\/td><td>Moderate\u2013High<\/td><\/tr>\n      <tr><td>Universal cell compatibility (any ABO)<\/td><td>Ja<\/td><td>Nein<\/td><td>Depends on mix<\/td><\/tr>\n      <tr><td>Preferred for CAR-T \/ ATMP<\/td><td>Ja<\/td><td>Not recommended<\/td><td>Not recommended<\/td><\/tr>\n    <\/tbody>\n  <\/table>\n\n  <div class=\"sb-pab-info\">\n    <p><strong>Plasma vs. Serum \u2014 Type AB Male:<\/strong> SeamlessBio also supplies <a href=\"https:\/\/seamlessbio.de\/de\/human-serum-otc-type-ab-male\/\" style=\"color:#18b7b2;\">Menschliches Serum, OTC, Typ AB, m\u00e4nnlich<\/a> \u2014 produced from whole blood without anticoagulant, so it lacks coagulation factors but contains higher concentrations of platelet-released growth factors. For cell culture where coagulation factor activity is not required, off-the-clot serum is often specified. For assays requiring intact factor activity, use plasma.<\/p>\n  <\/div>\n\n  <div class=\"sb-pab-specs\">\n    <h2>Product specifications<\/h2>\n    <table class=\"sb-pab-table\">\n      <tbody>\n        <tr><td>Article number<\/td><td>HPAB-M<\/td><\/tr>\n        <tr><td>Produkttyp<\/td><td>Human Plasma, Blood Group AB, Male Donors<\/td><\/tr>\n        <tr><td>Herkunft<\/td><td>EU or US \u2014 specify at order<\/td><\/tr>\n        <tr><td>Donor selection<\/td><td>Male donors only, blood group AB confirmed by typing<\/td><\/tr>\n        <tr><td>Anti-A \/ Anti-B antibodies<\/td><td>Absent \u2014 confirmed by ABO blood group typing<\/td><\/tr>\n        <tr><td>Anticoagulant<\/td><td>EDTA (K2) \u00b7 Citrate (3.2%) \u00b7 ACD-A \u2014 specify at order<\/td><\/tr>\n        <tr><td>Available formats<\/td><td>Single donor units (~200\u2013450 mL) \u00b7 Pooled AB male lots \u00b7 Bulk on request<\/td><\/tr>\n        <tr><td>Lagerung<\/td><td>Fresh-frozen \u221220\u00b0C \u00b7 \u221280\u00b0C on request<\/td><\/tr>\n        <tr><td>Virus-Screening<\/td><td>HIV-1\/2 Ab, HBsAg, HCV Ab, Syphilis \u2014 all negative<\/td><\/tr>\n        <tr><td>Dokumentation<\/td><td>CoA, CoO, MSDS, viral screening report \u00b7 GMP process documentation on request<\/td><\/tr>\n        <tr><td>Minimum order<\/td><td>No minimum order quantity<\/td><\/tr>\n        <tr><td>Zulassungsstatus<\/td><td>For research and IVD manufacturing use \u00b7 GMP process development documentation available<\/td><\/tr>\n      <\/tbody>\n    <\/table>\n  <\/div>\n\n  <div class=\"sb-pab-faq\">\n    <h2>Frequently asked questions<\/h2>\n    <div class=\"sb-pab-faq-item\">\n      <h3>Is AB male plasma available as single units or pooled lots \u2014 or both?<\/h3>\n      <p>Both. Single AB male donor units provide per-donor traceability and are suitable for reference panel construction. Pooled AB male lots (multiple AB male donors combined) provide a larger homogeneous volume for manufacturing and scale-up. State your preference and required volume at enquiry.<\/p>\n    <\/div>\n    <div class=\"sb-pab-faq-item\">\n      <h3>Which anticoagulant should I specify for CAR-T or NK cell expansion media?<\/h3>\n      <p>ACD-A (Acid Citrate Dextrose Formula A) is the preferred anticoagulant for cell therapy plasma used as a media supplement \u2014 less cytotoxic at typical usage concentrations than EDTA, and commonly specified in PBMC and NK cell protocols. EDTA is standard for IVD applications. Specify your requirement at order \u2014 all three formats are available.<\/p>\n    <\/div>\n    <div class=\"sb-pab-faq-item\">\n      <h3>Can this plasma support a GMP cell therapy manufacturing process?<\/h3>\n      <p>SeamlessBio AB male plasma is available with extended documentation to support GMP process development and manufacturing qualification \u2014 including TSE statements, donor consent documentation and manufacturing site certification where available. Discuss your specific regulatory submission requirements directly with us. Contact <a href=\"mailto:info@seamlessbio.de\" style=\"color:#18b7b2;\">info@seamlessbio.de<\/a>.<\/p>\n    <\/div>\n    <div class=\"sb-pab-faq-item\">\n      <h3>What is the difference between this product and Human Serum OTC Type AB Male?<\/h3>\n      <p>Plasma is collected with anticoagulant before centrifugation and retains all coagulation factors including fibrinogen. Off-the-clot serum is obtained after natural clotting \u2014 no coagulation factors remain, but platelets degranulate during clotting and release additional growth factors (PDGF, TGF-\u03b2) into the serum. For cell culture supplementation, serum is often preferred. For applications requiring intact coagulation factor activity, use plasma. See <a href=\"https:\/\/seamlessbio.de\/de\/human-serum-otc-type-ab-male\/\" style=\"color:#18b7b2;\">Menschliches Serum, OTC, Typ AB, m\u00e4nnlich \u2192<\/a><\/p>\n    <\/div>\n  <\/div>\n\n  <div class=\"sb-pab-cta\">\n    <h2>Not sure which AB male format fits your protocol?<\/h2>\n    <p>Contact our team \u2014 we advise on plasma vs. serum, anticoagulant format, single units vs. pooled lots, and provide a free test volume before you commit.<\/p>\n    <a class=\"sb-pab-btn-teal\" href=\"mailto:info@seamlessbio.de?subject=Human%20Plasma%20Type%20AB%20Male%20Enquiry\">Kontakt<\/a>\n  <\/div>\n\n<\/div>\t\t\t\t<\/div>\n\t\t\n<\/div>\n\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Home \/ Seren &amp; Plasma \/ Human Plasma \/ Human Plasma Type AB Male SeamlessBio \u2014 Human Plasma Human Plasma \u2014 Type AB, Male Donors Plasma from certified male AB [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_eb_attr":"","footnotes":""},"class_list":["post-2412","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.0 (Yoast SEO v28.0) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Human Plasma Type AB Male | EU &amp; US Origin | CAR-T &amp; Cell Therapy<\/title>\n<meta name=\"description\" content=\"Human plasma from male AB blood-type donors \u2014 no anti-A or anti-B antibodies. 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