{"id":2645,"date":"2026-07-14T09:22:44","date_gmt":"2026-07-14T08:22:44","guid":{"rendered":"https:\/\/seamlessbio.de\/?page_id=2645"},"modified":"2026-07-14T09:27:45","modified_gmt":"2026-07-14T08:27:45","slug":"human-processed-serum-hps","status":"publish","type":"page","link":"https:\/\/seamlessbio.de\/de\/human-processed-serum-hps\/","title":{"rendered":"Humanes verarbeitetes Serum (HPS)"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"2645\" class=\"elementor elementor-2645\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-17f7323 e-con e-atomic-element e-flexbox-base e-7a388c8 \" data-id=\"17f7323\" data-element_type=\"e-flexbox\" data-e-type=\"e-flexbox\" data-interaction-id=\"17f7323\" data-e-type=\"e-flexbox\" data-id=\"17f7323\">\n    \t\t<div class=\"elementor-element elementor-element-22370f0 elementor-widget elementor-widget-html\" data-id=\"22370f0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<!-- ============================================================\n  SEAMLESSBIO WORDPRESS \u2014 ELEMENTOR HTML WIDGET\n  PAGE: Human Processed Serum (HPS) \u2014 Vitamin D Depleted\n  URL SLUG: \/human-processed-serum-hps\/\n  PARENT: \/human-sera-plasma-and-more\/\n\n  YOAST SEO:\n  SEO Title:       Human Processed Serum HPS | Vitamin D Depleted | IVD | SeamlessBio\n  Slug:            human-processed-serum-hps\n  Focus Keyword:   human processed serum vitamin D depleted\n  Meta Description: Human Processed Serum (HPS) Vitamin D depleted \u2014 25-OH-D < 4 ng\/mL, charcoal stripped, 0.2 \u00b5m filtered. For Vitamin D IVD calibrator manufacturing, zero standard matrix and QC material. 100 mL to 10+ litres. EU supplier. No MOQ. SeamlessBio Germany.\n  \n  ADDITIONAL KEYWORDS:\n  - vitamin D depleted human serum supplier\n  - vitamin D free human serum IVD\n  - charcoal stripped serum vitamin D\n  - 25-OH-D depleted serum calibrator\n  - Vitamin D Serum depleted kaufen\n============================================================ -->\n\n<style>\n*,*::before,*::after{box-sizing:border-box}\n.sb-pp{font-family:-apple-system,BlinkMacSystemFont,\"Segoe UI\",Arial,sans-serif;font-size:16px;color:#1a2e35;line-height:1.65;max-width:1100px;margin:0 auto;padding:32px 20px 80px}\n.sb-pp-bc{font-size:14px;color:#888;margin-bottom:24px}\n.sb-pp-bc a{color:#18b7b2;text-decoration:none}\n.sb-pp-bc span{color:#888}\n.sb-pp-hero{background:linear-gradient(135deg,#18b7b2 0%,#a8e6e4 60%,#e8f9f8 100%);border-radius:20px;padding:56px 48px;display:grid;grid-template-columns:1fr 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0}\n.sb-pp-cta{background:#f5f7f7;border-radius:20px;padding:48px;text-align:center}\n.sb-pp-cta h2{font-size:26px;font-weight:800;color:#1a2e35;margin:0 0 12px}\n.sb-pp-cta p{font-size:15px;color:#555;margin:0 0 28px}\n.sb-pp-cta-btns{display:flex;justify-content:center;gap:14px;flex-wrap:wrap}\n.sb-pp-btn-teal{display:inline-block;background:#18b7b2;color:#fff!important;text-decoration:none!important;font-size:13px;font-weight:700;letter-spacing:.06em;text-transform:uppercase;padding:14px 28px;border-radius:50px}\n.sb-pp-btn-teal:hover{background:#139b97}\n.sb-pp-btn-outline-dark{display:inline-block;background:transparent;color:#1a2e35!important;border:2px solid #1a2e35;text-decoration:none!important;font-size:13px;font-weight:700;letter-spacing:.06em;text-transform:uppercase;padding:12px 26px;border-radius:50px}\n@media(max-width:900px){.sb-pp-hero{grid-template-columns:1fr;padding:36px 28px}.sb-pp-hero-img{display:none}.sb-pp-usps{grid-template-columns:1fr 1fr}.sb-pp-qs-grid{grid-template-columns:1fr 1fr}.sb-pp-twocol{grid-template-columns:1fr;gap:28px}}\n@media(max-width:600px){.sb-pp{padding:20px 16px 60px}.sb-pp-hero h1{font-size:26px}.sb-pp-hero-btns{flex-direction:column}.sb-pp-usps{grid-template-columns:1fr}.sb-pp-qs-grid{grid-template-columns:1fr}.sb-pp-cta{padding:32px 20px}.sb-pp-cta-btns{flex-direction:column}}\n<\/style>\n\n<div class=\"sb-pp\">\n\n<!-- BREADCRUMB -->\n<nav class=\"sb-pp-bc\">\n  <a href=\"https:\/\/seamlessbio.de\/\">Home<\/a> <span>\/<\/span>\n  <a href=\"https:\/\/seamlessbio.de\/human-sera-plasma-and-more\/\">Human Sera &amp; Plasma<\/a> <span>\/<\/span>\n  Human Processed Serum (HPS) \u2014 Vitamin D Depleted\n<\/nav>\n\n<!-- HERO -->\n<div class=\"sb-pp-hero\">\n  <div class=\"sb-pp-hero-left\">\n    <div class=\"sb-pp-hero-eyebrow\">IVD Calibrator Matrix \u00b7 Vitamin D Assay Development \u00b7 ISO 13485 \u00b7 EU Supplier<\/div>\n    <h1>Human Processed Serum (HPS)<br>Vitamin D Depleted<\/h1>\n    <p class=\"sb-pp-hero-desc\">Charcoal stripped human serum with 25-OH-D depleted to &lt; 4 ng\/mL \u2014 the standard zero-calibrator matrix for Vitamin D IVD assay kits. Also known as: Vitamin D free human serum \u00b7 Vitamin D stripped serum \u00b7 25-OH-D depleted serum. 100 mL to 10+ litres. Full viral screening. No minimum order.<\/p>\n    <div class=\"sb-pp-hero-btns\">\n      <a href=\"mailto:info@seamlessbio.de?subject=HPS%20Vitamin%20D%20Depleted%20Enquiry\" class=\"sb-pp-btn-dark\">Request Quote &amp; Specs<\/a>\n      <a href=\"https:\/\/seamlessbio.de\/human-sera-plasma-and-more\/\" class=\"sb-pp-btn-outline\">All Serum Products<\/a>\n    <\/div>\n  <\/div>\n  <div class=\"sb-pp-hero-img\">\n    <img decoding=\"async\" src=\"https:\/\/seamlessbio.de\/wp-content\/uploads\/2026\/07\/human-processed-serum-hps.png\"\n         alt=\"Human Processed Serum HPS Vitamin D Depleted IVD Calibrator SeamlessBio Germany\"\n         onerror=\"this.style.display='none'\">\n  <\/div>\n<\/div>\n\n<!-- USP CARDS -->\n<div class=\"sb-pp-usps\">\n  <div class=\"sb-pp-usp\">\n    <div class=\"sb-pp-usp-num\">01<\/div>\n    <h3>25-OH-D &lt; 4 ng\/mL<\/h3>\n    <p>Standard residual specification. Custom residual level available \u2014 specify your target at order. Lot-specific analytical data included.<\/p>\n  <\/div>\n  <div class=\"sb-pp-usp\">\n    <div class=\"sb-pp-usp-num\">02<\/div>\n    <h3>100 mL to 10+ L<\/h3>\n    <p>From evaluation volumes to full IVD manufacturing runs. Same documentation and traceability at every scale. No minimum order.<\/p>\n  <\/div>\n  <div class=\"sb-pp-usp\">\n    <div class=\"sb-pp-usp-num\">03<\/div>\n    <h3>Full Viral Screening<\/h3>\n    <p>HIV-1\/2, HBsAg, anti-HCV, Syphilis per lot. NAT screening on request. Complete donor traceability on file. CoA, CoO, TSE\/BSE included.<\/p>\n  <\/div>\n  <div class=\"sb-pp-usp\">\n    <div class=\"sb-pp-usp-num\">04<\/div>\n    <h3>EU Supplier \u00b7 IVDR Ready<\/h3>\n    <p>Based in Passau, Germany. IVDR documentation package on request. 5\u201310 day lead time to DACH. No import delays.<\/p>\n  <\/div>\n<\/div>\n\n<!-- TERMINOLOGY -->\n<div class=\"sb-pp-qs\">\n  <h2>Also known as \u2014 alternative terminology<\/h2>\n  <p style=\"font-size:15px;color:#444;margin:0 0 20px;line-height:1.7\">This product is referred to by different names in the IVD industry and scientific literature. SeamlessBio supplies all of the following under one product:<\/p>\n  <div class=\"sb-pp-qs-grid\">\n    <div class=\"sb-pp-qs-card\">\n      <div class=\"sb-pp-qs-card-label\">Industry standard term<\/div>\n      <div class=\"sb-pp-qs-card-link\">Human Processed Serum (HPS) Vitamin D Depleted<\/div>\n    <\/div>\n    <div class=\"sb-pp-qs-card\">\n      <div class=\"sb-pp-qs-card-label\">Used by Golden West Biologicals, Molecular Depot<\/div>\n      <div class=\"sb-pp-qs-card-link\">Vitamin D Free Human Serum<\/div>\n    <\/div>\n    <div class=\"sb-pp-qs-card\">\n      <div class=\"sb-pp-qs-card-label\">Used in clinical trial protocols<\/div>\n      <div class=\"sb-pp-qs-card-link\">Vitamin D Stripped Human Serum<\/div>\n    <\/div>\n    <div class=\"sb-pp-qs-card\">\n      <div class=\"sb-pp-qs-card-label\">Processing method descriptor<\/div>\n      <div class=\"sb-pp-qs-card-link\">Charcoal Stripped Serum \u2014 Vitamin D<\/div>\n    <\/div>\n    <div class=\"sb-pp-qs-card\">\n      <div class=\"sb-pp-qs-card-label\">Analyte-specific descriptor<\/div>\n      <div class=\"sb-pp-qs-card-link\">25-OH-D Depleted Human Serum<\/div>\n    <\/div>\n    <div class=\"sb-pp-qs-card\">\n      <div class=\"sb-pp-qs-card-label\">IVD manufacturing term<\/div>\n      <div class=\"sb-pp-qs-card-link\">Vitamin D Depleted Serum Calibrator Matrix<\/div>\n    <\/div>\n  <\/div>\n<\/div>\n\n<hr class=\"sb-pp-divider\">\n\n<!-- SPECS TABLE -->\n<div class=\"sb-pp-qs\">\n  <h2>Product Specifications<\/h2>\n  <div class=\"sb-pp-table-wrap\">\n  <table class=\"sb-pp-table\">\n    <tbody>\n      <tr><td>Product type<\/td><td>Human Processed Serum (HPS) \u2014 Vitamin D Depleted<\/td><\/tr>\n      <tr><td>Depletion method<\/td><td>Activated charcoal stripping (dextran-coated charcoal)<\/td><\/tr>\n      <tr><td>Residual 25-OH-D<\/td><td>&lt; 4 ng\/mL (standard) \u00b7 custom residual level on request<\/td><\/tr>\n      <tr><td>Anticoagulant \/ base<\/td><td>Serum (clot-based, no anticoagulant) \u2014 standard \u00b7 EDTA plasma base on request<\/td><\/tr>\n      <tr><td>Processing<\/td><td>Delipidated + Vitamin D depleted \u00b7 0.2 \u00b5m sterile filtered<\/td><\/tr>\n      <tr><td>Donor pool<\/td><td>Pooled, mixed gender \u00b7 full traceability on file<\/td><\/tr>\n      <tr><td>Viral screening<\/td><td>HIV-1\/2 Ab, HBsAg, anti-HCV Ab, Syphilis \u2014 per lot<\/td><\/tr>\n      <tr><td>NAT screening<\/td><td>HIV-1 RNA, HCV RNA, HBV DNA \u2014 on request<\/td><\/tr>\n      <tr><td>Storage<\/td><td>\u221220\u00b0C \u00b7 Shelf life 24 months from production date<\/td><\/tr>\n      <tr><td>Available volumes<\/td><td>100 mL \u00b7 500 mL \u00b7 1000 mL \u00b7 5 L \u00b7 10 L \u00b7 Bulk on request<\/td><\/tr>\n      <tr><td>Documentation<\/td><td>CoA \u00b7 CoO \u00b7 Viral screening report \u00b7 TSE\/BSE statement \u00b7 SDS<\/td><\/tr>\n      <tr><td>IVDR documentation<\/td><td>Extended viral panel \u00b7 NAT \u00b7 ISO 13485 certificate \u2014 on request<\/td><\/tr>\n      <tr><td>Intended use<\/td><td>Manufacture of in vitro diagnostic reagents \u00b7 Research use only<\/td><\/tr>\n      <tr><td>Minimum order<\/td><td>No minimum order quantity<\/td><\/tr>\n      <tr><td>Lead time<\/td><td>5\u201310 business days \u00b7 Large volumes (\u2265 5 L) on request<\/td><\/tr>\n    <\/tbody>\n  <\/table>\n  <\/div>\n<\/div>\n\n<hr class=\"sb-pp-divider\">\n\n<!-- TWO COL -->\n<div class=\"sb-pp-twocol\">\n  <div>\n    <h2>What is Human Processed Serum (HPS) Vitamin D Depleted?<\/h2>\n    <p>Human Processed Serum (HPS) Vitamin D depleted is pooled human serum that has been processed by activated charcoal stripping to remove endogenous 25-hydroxyvitamin D (25-OH-D\u2082 and 25-OH-D\u2083) and 1,25-dihydroxyvitamin D to residual levels below 4 ng\/mL. The matrix is also delipidated \u2014 lipoproteins removed to eliminate turbidity that would interfere with photometric assay measurements.<\/p>\n    <p>The result is a human serum background free of detectable Vitamin D \u2014 used as the zero-standard diluent and base matrix for Vitamin D IVD assay calibrator kits. Spiking defined concentrations of 25-OH-D\u2082 and\/or 25-OH-D\u2083 into this depleted matrix produces calibrators for the full assay range.<\/p>\n    <p>Compatible with automated immunoassay platforms (Roche Elecsys, Abbott Architect, DiaSorin LIAISON 25-OH-D, Siemens ADVIA Centaur) and LC-MS\/MS methods (isotope dilution, derivatisation-based). The human serum matrix provides endogenous binding protein background (Vitamin D Binding Protein, albumin) that matches patient samples \u2014 critical for assay accuracy across the full clinical range.<\/p>\n  <\/div>\n  <div>\n    <h3>Applications<\/h3>\n    <ul class=\"sb-pp-bullets\">\n      <li>Vitamin D IVD assay calibrator manufacturing \u2014 zero standard and calibrator matrix<\/li>\n      <li>25-OH-D\u2082 and 25-OH-D\u2083 kit development on automated immunoassay platforms<\/li>\n      <li>LC-MS\/MS method development \u2014 turbidity-free baseline for protein precipitation<\/li>\n      <li>QC material manufacturing \u2014 low, normal and high Vitamin D controls<\/li>\n      <li>Linearity studies \u2014 serial dilution from high-positive into depleted matrix<\/li>\n      <li>Interference studies \u2014 lipemia, haemolysis and icterus assessment (IVDR Annex I)<\/li>\n      <li>EQA and proficiency testing material production<\/li>\n      <li>1,25(OH)\u2082D (active Vitamin D) assay development<\/li>\n      <li>Vitamin D Binding Protein (DBP) assay development<\/li>\n      <li>Research \u2014 cell culture studies using Vitamin D-free human serum<\/li>\n    <\/ul>\n  <\/div>\n<\/div>\n\n<hr class=\"sb-pp-divider\">\n\n<!-- RELATED -->\n<div class=\"sb-pp-qs\">\n  <h2>Related Depleted &amp; Processed Serum Products<\/h2>\n  <div class=\"sb-pp-qs-grid\">\n    <a class=\"sb-pp-qs-card\" href=\"https:\/\/seamlessbio.de\/human-processed-serum-hps\/\">\n      <div class=\"sb-pp-qs-card-label\">Charcoal stripped \u00b7 25-OH-D &lt; 4 ng\/mL<\/div>\n      <div class=\"sb-pp-qs-card-link\">HPS Vitamin D Depleted \u2192 (this page)<\/div>\n    <\/a>\n    <a class=\"sb-pp-qs-card\" href=\"mailto:info@seamlessbio.de?subject=HPS%20Steroid%20Depleted\">\n      <div class=\"sb-pp-qs-card-label\">Endogenous steroids below detection<\/div>\n      <div class=\"sb-pp-qs-card-link\">HPS Steroid Depleted \u2192<\/div>\n    <\/a>\n    <a class=\"sb-pp-qs-card\" href=\"mailto:info@seamlessbio.de?subject=HPS%20Charcoal%20Stripped\">\n      <div class=\"sb-pp-qs-card-label\">Broad small-molecule depletion<\/div>\n      <div class=\"sb-pp-qs-card-link\">HPS Charcoal Stripped \u2192<\/div>\n    <\/a>\n    <a class=\"sb-pp-qs-card\" href=\"https:\/\/seamlessbio.de\/human-serum-delipidated\/\">\n      <div class=\"sb-pp-qs-card-label\">Lipoproteins removed \u00b7 turbidity-free<\/div>\n      <div class=\"sb-pp-qs-card-link\">Human Serum Delipidated \u2192<\/div>\n    <\/a>\n    <a class=\"sb-pp-qs-card\" href=\"https:\/\/seamlessbio.de\/human-serum\/\">\n      <div class=\"sb-pp-qs-card-label\">Standard pooled \u00b7 all variants<\/div>\n      <div class=\"sb-pp-qs-card-link\">Human Serum Standard \u2192<\/div>\n    <\/a>\n    <a class=\"sb-pp-qs-card\" href=\"mailto:info@seamlessbio.de?subject=Custom%20Depleted%20Serum\">\n      <div class=\"sb-pp-qs-card-label\">Custom residual level \u00b7 combined processing<\/div>\n      <div class=\"sb-pp-qs-card-link\">Custom Specification \u2192<\/div>\n    <\/a>\n  <\/div>\n<\/div>\n\n<hr class=\"sb-pp-divider\">\n\n<!-- FAQ -->\n<div class=\"sb-pp-faq\">\n  <h2>Frequently Asked Questions<\/h2>\n\n  <div class=\"sb-pp-faq-item\">\n    <h3>What is Human Processed Serum (HPS) and how does it differ from standard human serum?<\/h3>\n    <p>Human Processed Serum (HPS) is human serum that has undergone additional processing \u2014 typically delipidation and charcoal stripping to remove specific analytes such as Vitamin D, steroids or hormones to below assay detection limits. Standard human serum retains all endogenous analytes and is not suitable as a zero-calibrator base for Vitamin D assays. HPS Vitamin D depleted provides a human matrix with 25-OH-D removed to &lt; 4 ng\/mL \u2014 enabling accurate calibrator preparation across the full Vitamin D assay range.<\/p>\n  <\/div>\n\n  <div class=\"sb-pp-faq-item\">\n    <h3>Is \"Vitamin D free serum\", \"Vitamin D stripped serum\" and \"HPS Vitamin D depleted\" the same product?<\/h3>\n    <p>Yes \u2014 these terms describe the same product category. \"Vitamin D free human serum\" (used by Golden West Biologicals and Molecular Depot), \"Vitamin D stripped serum\" (used in clinical trial protocols), \"charcoal stripped serum Vitamin D\" and \"Human Processed Serum (HPS) Vitamin D depleted\" (SEQENS IVD \/ Avantor nomenclature) all refer to human serum processed by charcoal stripping to remove 25-OH-D to &lt; 4 ng\/mL. SeamlessBio supplies this product regardless of which terminology your specification uses.<\/p>\n  <\/div>\n\n  <div class=\"sb-pp-faq-item\">\n    <h3>What volumes are available \u2014 can I order 10 litres?<\/h3>\n    <p>Yes. SeamlessBio supplies HPS Vitamin D depleted from 100 mL evaluation volumes up to 10 litres and beyond for IVD manufacturing runs. Large volume orders (\u2265 1 L) are supplied with lot-specific CoA, full donor traceability and viral screening documentation. Batch reservation for production lifecycle supply is available without prepayment. Contact info@seamlessbio.de with your required volume and specification for a quote within 48 hours.<\/p>\n  <\/div>\n\n  <div class=\"sb-pp-faq-item\">\n    <h3>Can I specify a custom residual 25-OH-D level?<\/h3>\n    <p>Yes. Standard specification is residual 25-OH-D &lt; 4 ng\/mL (undetectable on most immunoassay platforms). Custom residual levels \u2014 for example &lt; 2 ng\/mL for LC-MS\/MS methods with lower detection limits, or a defined low concentration for spike-recovery validation \u2014 can be specified on request. Lot-specific Vitamin D analytical data is included with each shipment.<\/p>\n  <\/div>\n\n  <div class=\"sb-pp-faq-item\">\n    <h3>What documentation is included for IVDR technical files?<\/h3>\n    <p>Standard documentation per lot: Certificate of Analysis (CoA), Certificate of Origin (CoO), viral screening report (HIV-1\/2, HBsAg, anti-HCV, Syphilis), TSE\/BSE statement, Safety Data Sheet (SDS), complete donor traceability on file. Extended IVDR package on request: NAT screening (HIV-1 RNA, HCV RNA, HBV DNA), extended viral panel (anti-HBc, anti-HTLV, HAV Ab), ISO 13485 manufacturer certificate, IVDR Annex I Annex II documentation support.<\/p>\n  <\/div>\n\n  <div class=\"sb-pp-faq-item\">\n    <h3>Is this product suitable for use in IVD manufacturing?<\/h3>\n    <p>Yes. HPS Vitamin D depleted from SeamlessBio is intended for the manufacture of in vitro diagnostic reagents \u2014 calibrators, controls, standards and EQA specimens. Not for therapeutic use or direct administration to humans. Full IVD-grade documentation available. For GMP-grade material with extended documentation, contact info@seamlessbio.de.<\/p>\n  <\/div>\n<\/div>\n\n<!-- CTA -->\n<div class=\"sb-pp-cta\">\n  <h2>Request HPS Vitamin D Depleted<\/h2>\n  <p>Specify your required volume (100 mL to 10+ L), residual 25-OH-D level and documentation requirements \u2014 quote within 48 hours. Free evaluation sample available on request.<\/p>\n  <div class=\"sb-pp-cta-btns\">\n    <a href=\"mailto:info@seamlessbio.de?subject=HPS%20Vitamin%20D%20Depleted%20Enquiry\" class=\"sb-pp-btn-teal\">Request Quote &amp; Specifications<\/a>\n    <a href=\"https:\/\/seamlessbio.de\/human-sera-plasma-and-more\/\" class=\"sb-pp-btn-outline-dark\">All Serum Products \u2192<\/a>\n  <\/div>\n<\/div>\n\n<\/div>\n\n<!-- PRODUCT SCHEMA -->\n<script type=\"application\/ld+json\">\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"Product\",\n  \"name\": \"Human Processed Serum (HPS) \u2014 Vitamin D Depleted\",\n  \"description\": \"Human Processed Serum charcoal stripped with 25-OH-D depleted to < 4 ng\/mL. For Vitamin D IVD assay calibrator manufacturing, zero standard matrix and QC material production. 100 mL to 10+ litres. EU supplier. SeamlessBio Germany.\",\n  \"image\": \"https:\/\/seamlessbio.de\/wp-content\/uploads\/2026\/07\/human-processed-serum-hps.png\",\n  \"brand\": { \"@type\": \"Brand\", \"name\": \"SeamlessBio\" },\n  \"url\": \"https:\/\/seamlessbio.de\/human-processed-serum-hps\/\",\n  \"alternateName\": [\"Vitamin D free human serum\", \"Vitamin D stripped serum\", \"charcoal stripped serum vitamin D\", \"25-OH-D depleted serum\", \"Vitamin D depleted serum calibrator matrix\"],\n  \"offers\": {\n    \"@type\": \"Offer\",\n    \"url\": \"https:\/\/seamlessbio.de\/human-processed-serum-hps\/\",\n    \"priceCurrency\": \"EUR\",\n    \"price\": \"0\",\n    \"priceValidUntil\": \"2027-12-31\",\n    \"validFrom\": \"2026-01-01\",\n    \"availability\": \"https:\/\/schema.org\/InStock\",\n    \"seller\": { \"@type\": \"Organization\", \"name\": \"SeamlessBio GmbH\", \"url\": \"https:\/\/seamlessbio.de\" },\n    \"shippingDetails\": {\n      \"@type\": \"OfferShippingDetails\",\n      \"shippingRate\": { \"@type\": \"MonetaryAmount\", \"value\": \"0\", \"currency\": \"EUR\" },\n      \"shippingDestination\": { \"@type\": \"DefinedRegion\", \"addressCountry\": [\"DE\",\"AT\",\"CH\",\"NL\",\"BE\",\"FR\",\"IT\",\"ES\",\"PL\",\"CZ\",\"DK\",\"SE\",\"FI\",\"NO\",\"GB\"] },\n      \"deliveryTime\": {\n        \"@type\": \"ShippingDeliveryTime\",\n        \"handlingTime\": { \"@type\": \"QuantitativeValue\", \"minValue\": 1, \"maxValue\": 2, \"unitCode\": \"DAY\" },\n        \"transitTime\": { \"@type\": \"QuantitativeValue\", \"minValue\": 2, \"maxValue\": 5, \"unitCode\": \"DAY\" }\n      }\n    },\n    \"hasMerchantReturnPolicy\": {\n      \"@type\": \"MerchantReturnPolicy\",\n      \"applicableCountry\": \"DE\",\n      \"returnPolicyCategory\": \"https:\/\/schema.org\/MerchantReturnFiniteReturnWindow\",\n      \"merchantReturnDays\": 14,\n      \"returnMethod\": \"https:\/\/schema.org\/ReturnByMail\",\n      \"returnFees\": \"https:\/\/schema.org\/FreeReturn\"\n    }\n  }\n}\n<\/script>\n\n<!-- FAQ SCHEMA (AEO) -->\n<script type=\"application\/ld+json\">\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is Human Processed Serum HPS Vitamin D depleted?\",\n      \"acceptedAnswer\": { \"@type\": \"Answer\", \"text\": \"Human Processed Serum (HPS) Vitamin D depleted is pooled human serum charcoal stripped to remove 25-OH-D to residual levels below 4 ng\/mL. Used as zero-standard diluent and calibrator matrix for Vitamin D IVD assay kits on immunoassay platforms (Roche, Abbott, DiaSorin, Siemens) and LC-MS\/MS methods. Available from SeamlessBio from 100 mL to 10+ litres.\" }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Is Vitamin D free serum the same as HPS Vitamin D depleted?\",\n      \"acceptedAnswer\": { \"@type\": \"Answer\", \"text\": \"Yes. Vitamin D free human serum, Vitamin D stripped serum, charcoal stripped serum Vitamin D, 25-OH-D depleted serum and Human Processed Serum (HPS) Vitamin D depleted all describe the same product \u2014 human serum charcoal stripped to remove 25-OH-D to below 4 ng\/mL. SeamlessBio supplies this product regardless of which terminology is used.\" }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Where can I buy Human Processed Serum Vitamin D depleted in Europe?\",\n      \"acceptedAnswer\": { \"@type\": \"Answer\", \"text\": \"SeamlessBio (Passau, Germany) supplies HPS Vitamin D depleted for IVD calibrator and QC material manufacturing. Available from 100 mL to 10+ litres. Full viral screening, CoA, CoO, donor traceability and IVDR documentation available. Contact info@seamlessbio.de.\" }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Can I order 10 litres of Vitamin D depleted serum?\",\n      \"acceptedAnswer\": { \"@type\": \"Answer\", \"text\": \"Yes. SeamlessBio supplies HPS Vitamin D depleted up to 10 litres and beyond for IVD manufacturing. Batch reservation available without prepayment. Contact info@seamlessbio.de with your volume and specification for a quote within 48 hours.\" }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What documentation is available for IVDR technical files?\",\n      \"acceptedAnswer\": { \"@type\": \"Answer\", \"text\": \"Standard: CoA, CoO, viral screening report, TSE\/BSE statement, SDS. 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