{"id":2883,"date":"2026-08-22T15:45:34","date_gmt":"2026-08-22T14:45:34","guid":{"rendered":"https:\/\/wheat-quail-856400.hostingersite.com\/?page_id=2883"},"modified":"2026-11-02T16:25:59","modified_gmt":"2026-11-02T15:25:59","slug":"what-is-fbs","status":"publish","type":"page","link":"https:\/\/seamlessbio.de\/de\/what-is-fbs\/","title":{"rendered":"Was ist FKS"},"content":{"rendered":"<div data-elementor-type=\"wp-page\" data-elementor-id=\"2883\" class=\"elementor elementor-2883\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ce6d2f5 e-con e-atomic-element e-flexbox-base e-default-div e-db89372\" data-id=\"ce6d2f5\" data-element_type=\"e-flexbox\" data-e-type=\"e-flexbox\" data-interaction-id=\"ce6d2f5\">\n    \t\t<div class=\"elementor-element elementor-element-24116b7 elementor-widget elementor-widget-html\" data-id=\"24116b7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<!-- \nWORDPRESS PAGE \u2014 PASTE INTO GUTENBERG \"BENUTZERDEFINIERTES HTML\" BLOCK\nYoast SEO:\n  Slug: what-is-fbs\n  SEO Title: What is FBS (Fetal Bovine Serum)? \u2014 Definition & Uses | SeamlessBio\n  Meta Description: What is fetal bovine serum (FBS)? Definition, composition, grades, applications and why it is the most widely used cell culture supplement. Expert guide from SeamlessBio.\n  Focus Keyword: what is FBS fetal bovine serum\n  Meta Robots: index, follow\n  Page Type: Article\n-->\n\n<div style=\"background:#e9fbfa;border-left:4px solid #18b7b2;border-radius:0 8px 8px 0;padding:20px 24px;margin-bottom:32px;\">\n<p style=\"font-size:11px;font-weight:700;text-transform:uppercase;letter-spacing:1px;color:#139b97;margin-bottom:8px;\">Kurzdefinition<\/p>\n<p style=\"font-size:16px;margin:0;\"><strong>Was ist FKS (f\u00f6tales K\u00e4lberserum)?:<\/strong> F\u00f6tales K\u00e4lberserum (FKS) ist die zellfreie Fraktion des Blutes von Rinderf\u00f6ten und wird Zellkulturmedien als Zusatz beigef\u00fcgt, um Wachstum, Proliferation und \u00dcberleben der Zellen zu unterst\u00fctzen. Es ist der meistverwendete Serumzusatz in biomedizinischer Forschung und biopharmazeutischer Herstellung.<\/p>\n<!-- BUY BOX (SEO: links to buy pages) -->\n<div class=\"sb-buy-box\" style=\"border:1px solid #cfe9e6;background:#f4fbfa;border-radius:12px;padding:22px 26px;margin:28px auto;max-width:1200px;box-sizing:border-box\">\n<h2 style=\"font-size:22px;line-height:1.3;margin:0 0 6px\">Fetales K\u00e4lberserum (FKS) ab EU-Lager kaufen<\/h2>\n<p style=\"margin:0 0 14px\">Angebot oder kostenloses Testmuster anfordern \u2013 Lager in der EU, ohne Mindestmenge, Chargenreservierung bis zu 36 Monate.<\/p>\n<ul style=\"margin:0;padding-left:20px;columns:2 300px;column-gap:32px\">\n<li style=\"margin:0 0 6px\"><a href=\"https:\/\/seamlessbio.de\/de\/produkt\/fetales-kaelberserum-fks-suedamerika\/\">Fetales K\u00e4lberserum \u2013 Herkunft S\u00fcdamerika<\/a><\/li>\n<li style=\"margin:0 0 6px\"><a href=\"https:\/\/seamlessbio.de\/de\/produkt\/fetales-kaelberserum-fks-usa\/\">Fetales K\u00e4lberserum \u2013 Herkunft USA<\/a><\/li>\n<li style=\"margin:0 0 6px\"><a href=\"https:\/\/seamlessbio.de\/de\/produkt\/fetales-kaelberserum-fks-australien\/\">Fetales K\u00e4lberserum \u2013 Herkunft Australien<\/a><\/li>\n<li style=\"margin:0 0 6px\"><a href=\"https:\/\/seamlessbio.de\/de\/produkt\/fks-low-igg\/\">FKS Ultra Low IgG (&lt;5 \u00b5g\/ml)<\/a><\/li>\n<li style=\"margin:0 0 6px\"><a href=\"https:\/\/seamlessbio.de\/de\/produkt\/fks-tetrazyklinfrei-tet-free\/\">Tetrazyklinfreies FKS (Tet-free)<\/a><\/li>\n<li style=\"margin:0 0 6px\"><a href=\"https:\/\/seamlessbio.de\/de\/produkt\/fks-hitzeinaktiviert-usa-australien-suedamerika\/\">FKS hitzeinaktiviert<\/a><\/li>\n<li style=\"margin:0 0 6px\"><a href=\"https:\/\/seamlessbio.de\/de\/produkt\/fks-es-zell-getestet-suedamerika\/\">ES-Zell-getestetes FKS<\/a><\/li>\n<li style=\"margin:0 0 6px\"><a href=\"https:\/\/seamlessbio.de\/de\/produkt\/fks-low-endotoxin-suedamerika\/\">FKS Low Endotoxin (\u22645 EU\/ml)<\/a><\/li>\n<li style=\"margin:0 0 6px\"><a href=\"https:\/\/seamlessbio.de\/de\/produkt\/fks-maennlich-testosteron-definiert\/\">FKS m\u00e4nnlich \u2013 Testosteron-definiert<\/a><\/li>\n\n<\/ul>\n<p style=\"margin:14px 0 0\"><a href=\"https:\/\/seamlessbio.de\/de\/request-quote\/\" style=\"font-weight:600\">Angebot anfordern \u2192<\/a><\/p>\n<\/div>\n<!-- \/BUY BOX -->\n\n<\/div>\n\n<h2>Wof\u00fcr wird FKS verwendet?<\/h2>\n<p>FKS wird Basalmedien (DMEM, RPMI 1640, MEM, F-12) zugesetzt, um ein vollst\u00e4ndiges Wachstumsmedium herzustellen. Es liefert die komplexe Mischung aus Wachstumsfaktoren, Tr\u00e4gerproteinen und N\u00e4hrstoffen, die die meisten S\u00e4ugerzellen in vitro zum \u00dcberleben und zur Vermehrung brauchen. Ohne Serumzusatz bleiben die meisten Zelllinien h\u00f6chstens 24\u201348 Stunden vital.<\/p>\n\n<p>Wichtige Anwendungen sind: Erhaltung von Krebszelllinien, Prim\u00e4rzellkultur, Hybridomproduktion, Herstellung viraler Vektoren (AAV, Lentivirus, Adenovirus), Impfstoffproduktion, Stammzellforschung und Toxikologie-Assays.<\/p>\n\n<h2>Warum gibt es verschiedene FKS-Qualit\u00e4ten?<\/h2>\n<p>Standard-FKS enth\u00e4lt 50\u2013200 \u00b5g\/ml bovines IgG, 1\u201310 EU\/ml Endotoxin und Spuren von Tetrazyklin \u2013 alles Bestandteile, die bestimmte Assaytypen st\u00f6ren. Spezialqualit\u00e4ten entfernen oder reduzieren diese Bestandteile f\u00fcr Anwendungen, in denen sie die Ergebnisse verf\u00e4lschen w\u00fcrden:<\/p>\n<ul>\n  <li><strong>FKS Low Endotoxin (&lt;1 EU\/ml):<\/strong> f\u00fcr Zytokinassays, Wirkstoffscreening, AAV-Produktion<\/li>\n  <li><strong>FKS Low IgG (&lt;200 \u00b5g\/ml):<\/strong> f\u00fcr die Hybridom-mAb-Produktion mit Protein-A-Aufreinigung<\/li>\n  <li><strong>FKS Ultra Low IgG (&lt;5 \u00b5g\/ml):<\/strong> f\u00fcr die Produktion von Antik\u00f6rpern in Diagnostikqualit\u00e4t<\/li>\n  <li><strong>FKS hitzeinaktiviert:<\/strong> f\u00fcr komplementempfindliche Assays und die Embryokultur<\/li>\n  <li><strong>FKS tetrazyklinfrei:<\/strong> f\u00fcr induzierbare Expressionssysteme (Tet-On\/Tet-Off)<\/li>\n<\/ul>\n\n<h2>Alternativen zu FKS<\/h2>\n<p>F\u00fcr Anwendungen, die xenofreie oder tierkomponentenfreie Bedingungen erfordern, l\u00e4sst sich FKS durch humanes Thrombozytenlysat (hPL), humanes AB-Serum, rekombinantes humanes Albumin (rHSA) + definierte Wachstumsfaktoren oder chemisch definierte serumfreie Medien ersetzen. Die richtige Alternative h\u00e4ngt vom Zelltyp und den regulatorischen Anforderungen ab.<\/p>\n\n<h2>Wichtige Fakten<\/h2>\n<ul>\n<li>FKS wird bei der Schlachtung tr\u00e4chtiger K\u00fche von Rinderf\u00f6ten gewonnen \u2013 der F\u00f6tus wird entnommen und das Blut unter sterilen Bedingungen per Herzpunktion abgenommen<\/li>\n<li>Standard-FKS enth\u00e4lt Wachstumsfaktoren (IGF-1, EGF, FGF-2), Albumin, Transferrin, Fibronektin, Hormone, Lipide und Spurenelemente<\/li>\n<li>FKS wird im Zellkulturmedium in Konzentrationen von 5\u201320 % eingesetzt \u2013 10 % ist die h\u00e4ufigste Standardkonzentration<\/li>\n<li>S\u00fcdamerikanische Herkunft (Brasilien, Argentinien, Uruguay) ist der weltweite Standard \u2013 von der OIE als Gebiet mit vernachl\u00e4ssigbarem BSE-Risiko eingestuft<\/li>\n<li>In vielen Qualit\u00e4ten erh\u00e4ltlich: Standard, Low Endotoxin (&lt;1 EU\/ml), Low IgG (&lt;200 \u00b5g\/ml), Ultra Low IgG (&lt;5 \u00b5g\/ml), hitzeinaktiviert, gammabestrahlt, tetrazyklinfrei, ES-Zell-getestet<\/li>\n<li>Die Chargenvariabilit\u00e4t ist die wichtigste Einschr\u00e4nkung \u2013 f\u00fcr Studien von mehr als 3 Monaten Dauer wird eine Chargenreservierung empfohlen<\/li>\n<li>Das gesamte FKS von SeamlessBio wird in Deutschland verarbeitet und QC-gepr\u00fcft, mit vollst\u00e4ndigem CoA inklusive Sterilit\u00e4t, Mykoplasmen, Endotoxin, Viruspanel und Zellkultur-Leistungstest<\/li>\n<\/ul>\n\n<h2>Weiterlesen<\/h2>\n<ul>\n<li><a href=\"https:\/\/seamlessbio.de\/de\/ressourcen\/blog\/fbs-alternativen-leitfaden-zum-wechsel-des-serums\/\">FKS-Qualit\u00e4ten erkl\u00e4rt \u2013 welche ist die richtige?<\/a><\/li>\n<li><a href=\"https:\/\/seamlessbio.de\/de\/fbs-lot-testing-protocol\/\">Protokoll zur FKS-Chargenpr\u00fcfung<\/a><\/li>\n<li><a href=\"https:\/\/seamlessbio.de\/de\/fks-vs-humanserum\/\">FBS im Vergleich zu Humanserum<\/a><\/li>\n<li><a href=\"https:\/\/seamlessbio.de\/de\/what-is-heat-inactivated-fbs\/\">Was ist hitzeinaktiviertes FKS?<\/a><\/li>\n<li><a href=\"https:\/\/seamlessbio.de\/de\/anpassung-an-die-serumfreie-zellkultur\/\">Leitfaden zur Umstellung auf serumfrei<\/a><\/li>\n<\/ul>\n\n<div style=\"background:#f4f6f7;border-radius:12px;padding:32px;text-align:center;margin-top:40px;\">\n<p style=\"font-size:18px;font-weight:700;color:#1a2e35;margin-bottom:12px;\">FKS-Portfolio \u2013 alle Qualit\u00e4ten von SeamlessBio<\/p>\n<p style=\"color:#6b7f82;margin-bottom:20px;\">Kostenloses Muster oder Angebot innerhalb von 48 Stunden anfordern.<\/p>\n<a href=\"https:\/\/seamlessbio.de\/de\/fetales-kaelberserum\/\" style=\"background:#18b7b2;color:#fff;padding:12px 28px;border-radius:50px;font-size:13px;font-weight:700;text-decoration:none;\">Zum Produkt \u2192<\/a>\n&nbsp;&nbsp;\n<a href=\"https:\/\/seamlessbio.de\/de\/kontakt\/\" style=\"border:2px solid #18b7b2;color:#139b97;padding:10px 28px;border-radius:50px;font-size:13px;font-weight:700;text-decoration:none;\">Muster anfordern<\/a>\n<\/div>\n\n<p style=\"font-size:13px;color:#6b7f82;margin-top:32px;border-top:1px solid #d8e8e7;padding-top:16px;\">\n<em>SeamlessBio \u00b7 Passau, Deutschland \u00b7 <a href=\"mailto:info@seamlessbio.de\">info@seamlessbio.de<\/a> \u00b7 +49 851 37932226<\/em>\n<\/p>\t\t\t\t<\/div>\n\t\t\n<\/div>\n\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Quick Definition What is FBS (Fetal Bovine Serum)?: Fetal bovine serum (FBS) is the cell-free fraction of blood collected from bovine fetuses, used as a supplement in cell culture media to support cell growth, proliferation and survival. It is the most widely used serum supplement in biomedical research and biopharmaceutical manufacturing. Buy fetal bovine serum [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_templately_pack_id":"","_templately_imported_at":"","_templately_source":"","_templately_import_session_id":"","footnotes":""},"class_list":["post-2883","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>What is FBS (Fetal Bovine Serum)? \u2014 Definition &amp; Uses<\/title>\n<meta name=\"description\" content=\"What is fetal bovine serum (FBS)? Definition, composition, grades, applications and why it is the most widely used cell culture supplement. 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