{"id":2963,"date":"2026-08-22T21:02:25","date_gmt":"2026-08-22T20:02:25","guid":{"rendered":"https:\/\/wheat-quail-856400.hostingersite.com\/?page_id=2963"},"modified":"2026-10-20T15:49:59","modified_gmt":"2026-10-20T14:49:59","slug":"what-is-dialyzed-fbs","status":"publish","type":"page","link":"https:\/\/seamlessbio.de\/de\/what-is-dialyzed-fbs\/","title":{"rendered":"Was ist dialysiertes FBS?"},"content":{"rendered":"<div data-elementor-type=\"wp-page\" data-elementor-id=\"2963\" class=\"elementor elementor-2963\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ef0c654 e-con e-atomic-element e-flexbox-base e-default-div e-52479d0\" data-id=\"ef0c654\" data-element_type=\"e-flexbox\" data-e-type=\"e-flexbox\" data-interaction-id=\"ef0c654\">\n    \t\t<div class=\"elementor-element elementor-element-d4d1665 elementor-widget elementor-widget-html\" data-id=\"d4d1665\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<!-- \nWORDPRESS PAGE \u2014 GUTENBERG \"BENUTZERDEFINIERTES HTML\" BLOCK\nSlug: what-is-dialyzed-fbs\nSEO Title: What is Dialyzed FBS? \u2014 Definition & Metabolism Studies | SeamlessBio\nMeta Description: What is dialyzed FBS, what does dialysis remove from serum, and when is it needed for isotope labeling, metabolomics and serum-free transition?\nFocus Keyword: what is dialyzed FBS\nAdditional Keywords: dialyzed fetal bovine serum isotope labeling, dialyzed FBS metabolomics, dialyzed serum metabolism studies 13C\nMenu: Resources \u2192 Glossary\n-->\n<div style=\"background:#e9fbfa;border-left:4px solid #18b7b2;border-radius:0 8px 8px 0;padding:20px 24px;margin-bottom:32px;\">\n<p style=\"font-size:11px;font-weight:700;text-transform:uppercase;letter-spacing:1px;color:#139b97;margin-bottom:8px;\">Kurzdefinition<\/p>\n<p style=\"font-size:16px;margin:0;\"><strong>Was ist dialysiertes FKS?:<\/strong> Dialysiertes FKS ist f\u00f6tales K\u00e4lberserum, das per S\u00e4ulenfiltration gegen PBS dialysiert wurde. Dabei werden kleine Molek\u00fcle wie Aminos\u00e4uren, Glukose, Nukleotide, Vitamine, Lipide und kleine Hormone entfernt, w\u00e4hrend gro\u00dfe Proteine wie Albumin, Wachstumsfaktoren und IgG erhalten bleiben.<\/p>\n<\/div>\n<h2>Hauptanwendungen von dialysiertem FKS<\/h2>\n<p><strong>Markierung mit stabilen Isotopen (SILAC, \u00b9\u00b3C-Stoffwechselfluss):<\/strong> Standard-FKS enth\u00e4lt unmarkierte Aminos\u00e4uren, die den Isotopeneinbau verd\u00fcnnen, wenn \u00b9\u00b3C-Aminos\u00e4uren zugegeben werden. Dialysiertes FKS entfernt diese Hintergrund-Aminos\u00e4uren und erm\u00f6glicht einen effizienten Isotopeneinbau aus definierten Quellen \u2013 unverzichtbar f\u00fcr SILAC-Proteomik und \u00b9\u00b3C-MFA-Stoffwechselflussanalysen.<\/p>\n<p><strong>Metabolomik:<\/strong> In der LC-MS-Metabolomik erzeugen Serummetaboliten im Medium einen hohen Hintergrund, der intrazellul\u00e4re Metabolitenprofile \u00fcberdeckt. Dialysiertes FKS liefert Albumin und Wachstumsfaktoren, h\u00e4lt den Hintergrund an kleinen Molek\u00fclen aber gering.<\/p>\n<h2>Wichtige Fakten<\/h2>\n<ul>\n<li>Die Dialyse entfernt kleine Molek\u00fcle: Aminos\u00e4uren, Glukose, Nukleotide, Vitamine, kleine Lipide, Tetrazykline<\/li>\n<li>Erh\u00e4lt gro\u00dfe Proteine: Albumin (~66 kDa), IgG (~150 kDa), Wachstumsfaktoren, Transferrin (~79 kDa)<\/li>\n<li>Eingesetzt in Isotopenmarkierungsstudien (\u00b9\u00b3C, \u00b9\u2075N, \u00b2H, \u00b9\u2074C) \u2013 entfernt unmarkierte N\u00e4hrstoffe, die den Isotopeneinbau verd\u00fcnnen<\/li>\n<li>Eingesetzt in der Metabolomik \u2013 entfernt Serummetaboliten, die intrazellul\u00e4re Metabolitenprofile in der LC-MS \u00fcberdecken<\/li>\n<li>Eingesetzt in Serumentzugsstudien \u2013 entfernt Glukose und Aminos\u00e4uren f\u00fcr definierte Mangelbedingungen<\/li>\n<li>Wachstumsf\u00f6rdernde Wirkung teilweise erhalten \u2013 Albumin und Wachstumsfaktoren bleiben erhalten; der Aminos\u00e4ureentzug erfordert eine Supplementierung<\/li>\n<\/ul>\n<h2>Weiterlesen<\/h2>\n<ul>\n<li><a href=\"https:\/\/seamlessbio.de\/de\/what-is-fbs\/\">Was ist FBS?<\/a><\/li>\n<li><a href=\"https:\/\/seamlessbio.de\/de\/ressourcen\/blog\/in-vitro-drug-metabolism-cyp450-microsomes-hepatocytes\/\">In-vitro-Wirkstoffmetabolismus \u2013 Leitfaden zur Matrix<\/a><\/li>\n<li><a href=\"https:\/\/seamlessbio.de\/de\/ressourcen\/guides\/anpassung-an-die-serumfreie-zellkultur\/\">Protokoll zur serumfreien Adaptation<\/a><\/li>\n<\/ul>\n<div style=\"background:#f4f6f7;border-radius:12px;padding:32px;text-align:center;margin-top:40px;\">\n<p style=\"font-size:18px;font-weight:700;color:#1a2e35;margin-bottom:12px;\">Dialysiertes FKS \u2013 auf Anfrage bei SeamlessBio<\/p>\n<a href=\"https:\/\/seamlessbio.de\/de\/kontakt\/\" style=\"background:#18b7b2;color:#fff;padding:12px 28px;border-radius:50px;font-size:13px;font-weight:700;text-decoration:none;\">Zum Produkt \u2192<\/a>\n&nbsp;&nbsp;\n<a href=\"https:\/\/seamlessbio.de\/de\/kontakt\/\" style=\"border:2px solid #18b7b2;color:#139b97;padding:10px 28px;border-radius:50px;font-size:13px;font-weight:700;text-decoration:none;\">Muster anfordern<\/a>\n<\/div>\n<p style=\"font-size:13px;color:#6b7f82;margin-top:32px;border-top:1px solid #d8e8e7;padding-top:16px;\">\n<em>SeamlessBio GmbH \u00b7 Passau, Deutschland \u00b7 <a href=\"mailto:info@seamlessbio.de\">info@seamlessbio.de<\/a><\/em>\n<\/p>\t\t\t\t<\/div>\n\t\t\n<\/div>\n\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Quick Definition What is Dialyzed FBS?: Dialyzed FBS is fetal bovine serum dialysed against PBS by column filtration, removing small molecules including amino acids, glucose, nucleotides, vitamins, lipids and small hormones while retaining large proteins such as albumin, growth factors and IgG. Primary applications for dialyzed FBS Stable isotope labeling (SILAC, \u00b9\u00b3C metabolic flux): Standard [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_templately_pack_id":"","_templately_imported_at":"","_templately_source":"","_templately_import_session_id":"","footnotes":""},"class_list":["post-2963","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>What is Dialyzed FBS? \u2014 Definition &amp; Metabolism Studies<\/title>\n<meta name=\"description\" content=\"What is dialyzed FBS, what does dialysis remove from serum, and when is it needed for isotope labeling, metabolomics and serum-free transition?\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/seamlessbio.de\/de\/what-is-dialyzed-fbs\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"What is Dialyzed FBS? \u2014 Definition &amp; Metabolism Studies\" \/>\n<meta property=\"og:description\" content=\"What is dialyzed FBS, what does dialysis remove from serum, and when is it needed for isotope labeling, metabolomics and serum-free transition?\" \/>\n<meta property=\"og:url\" content=\"https:\/\/seamlessbio.de\/de\/what-is-dialyzed-fbs\/\" \/>\n<meta property=\"og:site_name\" content=\"SeamlessBio\" \/>\n<meta property=\"article:modified_time\" content=\"2026-10-20T14:49:59+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/seamlessbio.de\/wp-content\/uploads\/2026\/04\/134428046.png\" \/>\n\t<meta property=\"og:image:width\" content=\"973\" \/>\n\t<meta property=\"og:image:height\" content=\"288\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Gesch\u00e4tzte Lesezeit\" \/>\n\t<meta name=\"twitter:data1\" content=\"2\u00a0Minuten\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/seamlessbio.de\\\/what-is-dialyzed-fbs\\\/\",\"url\":\"https:\\\/\\\/seamlessbio.de\\\/what-is-dialyzed-fbs\\\/\",\"name\":\"What is Dialyzed FBS? \u2014 Definition & Metabolism Studies\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/seamlessbio.de\\\/#website\"},\"datePublished\":\"2026-08-22T20:02:25+00:00\",\"dateModified\":\"2026-10-20T14:49:59+00:00\",\"description\":\"What is dialyzed FBS, what does dialysis remove from serum, and when is it needed for isotope labeling, metabolomics and serum-free transition?\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/seamlessbio.de\\\/what-is-dialyzed-fbs\\\/#breadcrumb\"},\"inLanguage\":\"de\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/seamlessbio.de\\\/what-is-dialyzed-fbs\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/seamlessbio.de\\\/what-is-dialyzed-fbs\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Start\",\"item\":\"https:\\\/\\\/seamlessbio.de\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"What is Dialyzed FBS?\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/seamlessbio.de\\\/#website\",\"url\":\"https:\\\/\\\/seamlessbio.de\\\/\",\"name\":\"SeamlessBio\",\"description\":\"Human serum, plasma and hPL, single-use bioprocessing bags, serum-free media, animal sera and FBS. 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