{"id":2983,"date":"2026-08-22T21:05:09","date_gmt":"2026-08-22T20:05:09","guid":{"rendered":"https:\/\/seamlessbio.de\/?page_id=2983"},"modified":"2026-08-23T00:37:28","modified_gmt":"2026-08-22T23:37:28","slug":"what-is-human-plasma","status":"publish","type":"page","link":"https:\/\/seamlessbio.de\/de\/what-is-human-plasma\/","title":{"rendered":"What is Human Plasma?"},"content":{"rendered":"
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Quick Definition<\/p>\n

What is Human Plasma?:<\/strong> Human plasma is the liquid component of blood collected with an anticoagulant (EDTA, heparin, or citrate) before clotting, then separated from blood cells by centrifugation. Unlike serum \u2014 collected after clotting \u2014 plasma retains fibrinogen, coagulation factors, and platelet-derived proteins at near-physiological concentrations.<\/p>\n<\/div>\n

When to use plasma instead of serum<\/h2>\n

Use plasma when the analyte is present in plasma but absent or degraded in serum (coagulation factors, fibrinogen); when the assay requires absence of platelet activation products; or when the application requires clotting factors (coagulation research, thrombin generation, fibrinolysis studies).<\/p>\n

Apheresis plasma<\/h2>\n

Apheresis plasma is collected by automated plasmapheresis \u2014 donor blood cells are returned while only plasma is collected, enabling 500\u2013800 mL per donation vs 200\u2013250 mL from whole blood. Available from SeamlessBio on request for large-volume IVD and clinical applications.<\/p>\n

Key Facts<\/h2>\n