{"id":2993,"date":"2026-08-22T21:06:17","date_gmt":"2026-08-22T20:06:17","guid":{"rendered":"https:\/\/wheat-quail-856400.hostingersite.com\/?page_id=2993"},"modified":"2026-11-02T16:25:12","modified_gmt":"2026-11-02T15:25:12","slug":"what-is-horse-serum","status":"publish","type":"page","link":"https:\/\/seamlessbio.de\/de\/what-is-horse-serum\/","title":{"rendered":"Was ist Pferdeserum?"},"content":{"rendered":"<div data-elementor-type=\"wp-page\" data-elementor-id=\"2993\" class=\"elementor elementor-2993\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4df23e1 e-con e-atomic-element e-flexbox-base e-default-div e-26c46c0\" data-id=\"4df23e1\" data-element_type=\"e-flexbox\" data-e-type=\"e-flexbox\" data-interaction-id=\"4df23e1\">\n    \t\t<div class=\"elementor-element elementor-element-7d0cc30 elementor-widget elementor-widget-html\" data-id=\"7d0cc30\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<!-- \nWORDPRESS PAGE \u2014 GUTENBERG \"BENUTZERDEFINIERTES HTML\" BLOCK\nSlug: what-is-horse-serum\nSEO Title: What is Horse Serum? \u2014 Definition & Cell Culture Uses | SeamlessBio\nMeta Description: What is horse serum, when is it used in cell culture and IHC blocking, and how does it differ from FBS and other animal sera?\nFocus Keyword: what is horse serum cell culture\nAdditional Keywords: horse serum blocking IHC, equine serum cell culture, horse serum hybridoma, normal horse serum NHS\nMenu: Resources \u2192 Glossary\n-->\n<div style=\"background:#e9fbfa;border-left:4px solid #18b7b2;border-radius:0 8px 8px 0;padding:20px 24px;margin-bottom:32px;\">\n<p style=\"font-size:11px;font-weight:700;text-transform:uppercase;letter-spacing:1px;color:#139b97;margin-bottom:8px;\">Kurzdefinition<\/p>\n<p style=\"font-size:16px;margin:0;\"><strong>Was ist Pferdeserum?<\/strong> Pferdeserum (Equines Serum) wird von adulten Pferden gewonnen und in der Zellkultur als Zusatz f\u00fcr bestimmte Zelltypen eingesetzt, in IHC und Immunfluoreszenz als Blockierreagenz bei im Pferd oder Esel hergestellten Sekund\u00e4rantik\u00f6rpern sowie in der equinen Reproduktionsbiologie f\u00fcr Eizellreifung und Embryokultur.<\/p>\n<!-- BUY BOX (SEO: links to buy pages) -->\n<div class=\"sb-buy-box\" style=\"border:1px solid #cfe9e6;background:#f4fbfa;border-radius:12px;padding:22px 26px;margin:28px auto;max-width:1200px;box-sizing:border-box\">\n<h2 style=\"font-size:22px;line-height:1.3;margin:0 0 6px\">Tierseren ab EU-Lager kaufen<\/h2>\n<p style=\"margin:0 0 14px\">Angebot anfragen \u2013 EU-Lager, Chargendokumentation, Chargenreservierung bis zu 36 Monate.<\/p>\n<ul style=\"margin:0;padding-left:20px;columns:2 300px;column-gap:32px\">\n<li style=\"margin:0 0 6px\"><a href=\"https:\/\/seamlessbio.de\/de\/produkt\/pferdeserum-eu-sterilfiltriert\/\" style=\"font-weight:700\">Pferdeserum \u2013 EU-Herkunft<\/a><\/li>\n<li style=\"margin:0 0 6px\"><a href=\"https:\/\/seamlessbio.de\/de\/produkt\/spender-pferdeserum-dhs-eu\/\" style=\"font-weight:700\">Pferdeserum von Spendern (DHS)<\/a><\/li>\n<li style=\"margin:0 0 6px\"><a href=\"https:\/\/seamlessbio.de\/de\/produkt\/neugeborenen-kaelberserum-ncs-usa\/\">Neugeborenen-K\u00e4lberserum (NCS) \u2013 Herkunft USA<\/a><\/li>\n<li style=\"margin:0 0 6px\"><a href=\"https:\/\/seamlessbio.de\/de\/produkt\/neugeborenen-kaelberserum-ncs-australien\/\">Neugeborenen-K\u00e4lberserum (NCS) \u2013 Herkunft Australien<\/a><\/li>\n<li style=\"margin:0 0 6px\"><a href=\"https:\/\/seamlessbio.de\/de\/produkt\/kaelberserum-cs-usa-sterilfiltriert\/\">K\u00e4lberserum (CS) \u2013 Herkunft USA<\/a><\/li>\n<li style=\"margin:0 0 6px\"><a href=\"https:\/\/seamlessbio.de\/de\/produkt\/kaelberserum-cs-australien-sterilfiltriert\/\">K\u00e4lberserum (CS) \u2013 Herkunft Australien<\/a><\/li>\n<li style=\"margin:0 0 6px\"><a href=\"https:\/\/seamlessbio.de\/de\/produkt\/ziegenserum-normal-ngs-eu\/\">Normales Ziegenserum (NGS)<\/a><\/li>\n<li style=\"margin:0 0 6px\"><a href=\"https:\/\/seamlessbio.de\/de\/produkt\/eselserum-eu-sterilfiltriert\/\">Normales Eselserum<\/a><\/li>\n<li style=\"margin:0 0 6px\"><a href=\"https:\/\/seamlessbio.de\/de\/produkt\/kaninchenserum-normal-nrs-eu\/\">Normales Kaninchenserum (NRS)<\/a><\/li>\n<li style=\"margin:0 0 6px\"><a href=\"https:\/\/seamlessbio.de\/de\/produkt\/meerschweinchenserum-komplement\/\">Meerschweinchenserum \u2013 Komplementquelle<\/a><\/li>\n<li style=\"margin:0 0 6px\"><a href=\"https:\/\/seamlessbio.de\/de\/produkt\/mausserum-normal-nms-eu\/\">Normales Mausserum<\/a><\/li>\n<li style=\"margin:0 0 6px\"><a href=\"https:\/\/seamlessbio.de\/de\/produkt\/rattenserum-eu-sterilfiltriert\/\">Ratten-Serum<\/a><\/li>\n<li style=\"margin:0 0 6px\"><a href=\"https:\/\/seamlessbio.de\/de\/produkte\/seren-anderer-tiere\/\">Alle Tierseren \u2013 16 Tierarten<\/a><\/li>\n<\/ul>\n<p style=\"margin:14px 0 0\"><a href=\"https:\/\/seamlessbio.de\/de\/request-quote\/\" style=\"font-weight:600\">Angebot anfordern \u2192<\/a><\/p>\n<\/div>\n<!-- \/BUY BOX -->\n\n<\/div>\n<h2>Pferdeserum f\u00fcr die Myoblastendifferenzierung<\/h2>\n<p>Die h\u00e4ufigste Anwendung von Pferdeserum in der Zellbiologie ist die Myoblastendifferenzierung. C2C12-Zellen werden in DMEM + 10\u201320 % FKS expandiert und dann auf DMEM + 2 % Pferdeserum umgestellt. Die Umstellung l\u00f6st den Austritt aus dem Zellzyklus und eine MyoD-gesteuerte Myogenin-Expression aus, die innerhalb von 5\u20137 Tagen zur Bildung von Myotuben f\u00fchrt. Das niedrig konzentrierte Pferdeserum erh\u00e4lt die Viabilit\u00e4t ohne den mitogenen FKS-Reiz, der die Differenzierung verhindern w\u00fcrde.<\/p>\n<h2>Pferdeserum als Blockierreagenz in der IHC<\/h2>\n<p>Normales Pferdeserum (NHS) wird verwendet, wenn der Sekund\u00e4rantik\u00f6rper im Pferd oder Esel hergestellt wurde. Die Spezies des Blockierserums muss der Spezies des Sekund\u00e4rantik\u00f6rpers entsprechen. Empfohlen: 5\u201310 % NHS in PBS, 30\u201360 Minuten vor dem Auftragen des Prim\u00e4rantik\u00f6rpers.<\/p>\n<h2>Wichtige Fakten<\/h2>\n<ul>\n<li>Eingesetzt als Blockierserum (normales Pferdeserum, NHS), wenn der Sekund\u00e4rantik\u00f6rper im Pferd oder Esel hergestellt wurde<\/li>\n<li>Eingesetzt in Differenzierungsmedien f\u00fcr Muskelzellen \u2013 2 % Pferdeserum ist Standard, um die Differenzierung von Myoblasten zu Myotuben einzuleiten<\/li>\n<li>Eingesetzt in der equinen IVF \u2013 Medien f\u00fcr Eizellreifung und Embryohaltung verwenden Pferdeserum als speziesgleichen Zusatz<\/li>\n<li>Geringerer Wachstumsfaktorgehalt als FKS \u2013 2 % Pferdeserum unterdr\u00fcckt gezielt die Proliferation, um die Differenzierung von C2C12 und prim\u00e4ren Myoblasten einzuleiten<\/li>\n<li>Erh\u00e4ltlich bei SeamlessBio: 50 ml, 100 ml, 500 ml; hitzeinaktiviert auf Anfrage<\/li>\n<\/ul>\n<h2>Weiterlesen<\/h2>\n<ul>\n<li><a href=\"https:\/\/seamlessbio.de\/de\/ressourcen\/blog\/normal-serum-ihc-if-blocking-guide\/\">Leitfaden: Normalserum zum Blocken in IHC\/IF<\/a><\/li>\n<li><a href=\"https:\/\/seamlessbio.de\/de\/anwendungen\/fortpflanzung-bei-tieren\/\">Leitfaden Tierreproduktion &amp; IVF<\/a><\/li>\n<li><a href=\"https:\/\/seamlessbio.de\/de\/produkte\/animal-sera\/\">Tierseren-Portfolio<\/a><\/li>\n<\/ul>\n<div style=\"background:#f4f6f7;border-radius:12px;padding:32px;text-align:center;margin-top:40px;\">\n<p style=\"font-size:18px;font-weight:700;color:#1a2e35;margin-bottom:12px;\">Pferdeserum \u2013 erh\u00e4ltlich bei SeamlessBio<\/p>\n<a href=\"https:\/\/seamlessbio.de\/de\/produkte\/animal-sera\/\" style=\"background:#18b7b2;color:#fff;padding:12px 28px;border-radius:50px;font-size:13px;font-weight:700;text-decoration:none;\">Zum Produkt \u2192<\/a>\n&nbsp;&nbsp;\n<a href=\"https:\/\/seamlessbio.de\/de\/kontakt\/\" style=\"border:2px solid #18b7b2;color:#139b97;padding:10px 28px;border-radius:50px;font-size:13px;font-weight:700;text-decoration:none;\">Muster anfordern<\/a>\n<\/div>\n<p style=\"font-size:13px;color:#6b7f82;margin-top:32px;border-top:1px solid #d8e8e7;padding-top:16px;\">\n<em>SeamlessBio \u00b7 Passau, Deutschland \u00b7 <a href=\"mailto:info@seamlessbio.de\">info@seamlessbio.de<\/a><\/em>\n<\/p>\t\t\t\t<\/div>\n\t\t\n<\/div>\n\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Quick Definition What is Horse Serum?: Horse serum (equine serum) is serum collected from adult horses, used in cell culture as a supplement for specific cell types, in IHC and immunofluorescence as a blocking reagent when secondary antibodies are raised in horse or donkey, and in equine reproductive biology for oocyte maturation and embryo culture. [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_templately_pack_id":"","_templately_imported_at":"","_templately_source":"","_templately_import_session_id":"","footnotes":""},"class_list":["post-2993","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>What is Horse Serum? \u2014 Definition &amp; Cell Culture Uses<\/title>\n<meta name=\"description\" content=\"What is horse serum, when is it used in cell culture and IHC blocking, and how does it differ from FBS and other animal sera?\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/seamlessbio.de\/de\/what-is-horse-serum\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"What is Horse Serum? \u2014 Definition &amp; Cell Culture Uses\" \/>\n<meta property=\"og:description\" content=\"What is horse serum, when is it used in cell culture and IHC blocking, and how does it differ from FBS and other animal sera?\" \/>\n<meta property=\"og:url\" content=\"https:\/\/seamlessbio.de\/de\/what-is-horse-serum\/\" \/>\n<meta property=\"og:site_name\" content=\"SeamlessBio\" \/>\n<meta property=\"article:modified_time\" content=\"2026-11-02T15:25:12+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/seamlessbio.de\/wp-content\/uploads\/2026\/04\/134428046.png\" \/>\n\t<meta property=\"og:image:width\" content=\"973\" \/>\n\t<meta property=\"og:image:height\" content=\"288\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Gesch\u00e4tzte Lesezeit\" \/>\n\t<meta name=\"twitter:data1\" content=\"2\u00a0Minuten\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/seamlessbio.de\\\/what-is-horse-serum\\\/\",\"url\":\"https:\\\/\\\/seamlessbio.de\\\/what-is-horse-serum\\\/\",\"name\":\"What is Horse Serum? \u2014 Definition & Cell Culture Uses\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/seamlessbio.de\\\/#website\"},\"datePublished\":\"2026-08-22T20:06:17+00:00\",\"dateModified\":\"2026-11-02T15:25:12+00:00\",\"description\":\"What is horse serum, when is it used in cell culture and IHC blocking, and how does it differ from FBS and other animal sera?\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/seamlessbio.de\\\/what-is-horse-serum\\\/#breadcrumb\"},\"inLanguage\":\"de\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/seamlessbio.de\\\/what-is-horse-serum\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/seamlessbio.de\\\/what-is-horse-serum\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Start\",\"item\":\"https:\\\/\\\/seamlessbio.de\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"What is Horse Serum?\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/seamlessbio.de\\\/#website\",\"url\":\"https:\\\/\\\/seamlessbio.de\\\/\",\"name\":\"SeamlessBio\",\"description\":\"Human serum, plasma and hPL, single-use bioprocessing bags, serum-free media, animal sera and FBS. 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