{"id":3013,"date":"2026-08-22T21:08:47","date_gmt":"2026-08-22T20:08:47","guid":{"rendered":"https:\/\/wheat-quail-856400.hostingersite.com\/?page_id=3013"},"modified":"2026-08-23T00:23:22","modified_gmt":"2026-08-22T23:23:22","slug":"what-is-bsa-bovine-serum-albumin","status":"publish","type":"page","link":"https:\/\/seamlessbio.de\/de\/what-is-bsa-bovine-serum-albumin\/","title":{"rendered":"Was ist BSA (Rinderserumalbumin)?"},"content":{"rendered":"<div data-elementor-type=\"wp-page\" data-elementor-id=\"3013\" class=\"elementor elementor-3013\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f98f75d e-con e-atomic-element e-flexbox-base e-default-div e-e33bb46\" data-id=\"f98f75d\" data-element_type=\"e-flexbox\" data-e-type=\"e-flexbox\" data-interaction-id=\"f98f75d\">\n    \t\t<div class=\"elementor-element elementor-element-4416002 elementor-widget elementor-widget-html\" data-id=\"4416002\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<!-- \nWORDPRESS PAGE \u2014 GUTENBERG \"BENUTZERDEFINIERTES HTML\" BLOCK\nSlug: what-is-bsa-bovine-serum-albumin\nSEO Title: What is BSA (Bovine Serum Albumin)? \u2014 Definition & Uses | SeamlessBio\nMeta Description: What is BSA (bovine serum albumin), what does it do in cell culture and assay buffers, and which grade do you need? Complete definition from SeamlessBio.\nFocus Keyword: what is BSA bovine serum albumin\nAdditional Keywords: BSA bovine serum albumin cell culture blocking, what does BSA do ELISA, BSA grades standard fatty acid free low endotoxin\nMenu: Resources \u2192 Glossary\n-->\n<div style=\"background:#e9fbfa;border-left:4px solid #18b7b2;border-radius:0 8px 8px 0;padding:20px 24px;margin-bottom:32px;\">\n<p style=\"font-size:11px;font-weight:700;text-transform:uppercase;letter-spacing:1px;color:#139b97;margin-bottom:8px;\">Kurzdefinition<\/p>\n<p style=\"font-size:16px;margin:0;\"><strong>Was ist BSA (bovines Serumalbumin)?:<\/strong> Bovines Serumalbumin (BSA) ist das h\u00e4ufigste Protein im Rinderserum (~60 % des Gesamtproteins); es wird aus Rinderplasma gewonnen und auf &gt;96 % Reinheit aufgereinigt. BSA ist der am h\u00e4ufigsten verwendete Proteinzusatz in der Biochemie \u2013 als Blockierungsreagenz im ELISA, als Tr\u00e4gerprotein in serumfreien Medien, als Enzymstabilisator und als Wirkstoffbindungsprotein in DMPK-Assays.<\/p>\n<\/div>\n<h2>BSA-Qualit\u00e4ten \u2013 welche brauchen Sie?<\/h2>\n<p><strong>Standard-BSA:<\/strong> Blocking im ELISA und Western Blot, Antik\u00f6rperverd\u00fcnnung, allgemeiner Proteinstandard \u2013 am kosteng\u00fcnstigsten f\u00fcr unkritische Anwendungen mit hohem Verbrauch.<\/p>\n<p><strong>BSA Low Endotoxin (&lt;1 EU\/mg):<\/strong> Zellbasierte Assays, Zytokinassays, Rezeptorbindungsstudien \u2013 Standard-BSA enth\u00e4lt durch Kontamination mit gramnegativen Bakterien bei der Verarbeitung 1\u2013100 EU\/mg Endotoxin.<\/p>\n<p><strong>BSA fetts\u00e4urefrei (FAF):<\/strong> PPAR- und Kernrezeptorassays, IVF-Befruchtungsmedium, Korrektur der mikrosomalen Proteinbindung im DMPK (fu,mic) \u2013 Fetts\u00e4uren in Standard-BSA aktivieren Rezeptoren unspezifisch.<\/p>\n<h2>BSA vs. rHSA<\/h2>\n<p>BSA f\u00fcr nicht-humane Zelllinien, allgemeines Blocking und die DMPK-fu,mic-Korrektur. rHSA f\u00fcr die xenofreie ATMP-Herstellung, humanrelevante DMPK-fu,plasma-Messungen und GMP-Zellkultur.<\/p>\n<h2>Wichtige Fakten<\/h2>\n<ul>\n<li>H\u00e4ufigstes Protein im Rinderserum, MW ~66,5 kDa<\/li>\n<li>Hauptfunktionen: Fetts\u00e4uretr\u00e4ger, Wirkstoffbindung (Site I Warfarin, Site II Diazepam), Radikalf\u00e4nger (ROS), osmotischer Druck<\/li>\n<li>Eingesetzt zum ELISA-Blocking mit 1\u20135 % BSA\/PBS \u2013 s\u00e4ttigt unspezifische Proteinbindungsstellen auf Kunststoffoberfl\u00e4chen<\/li>\n<li>Eingesetzt in serumfreier Zellkultur mit 1\u20135 mg\/ml, um die Albuminfunktion von FKS zu ersetzen<\/li>\n<li>Drei wichtige Qualit\u00e4ten: Standard (&gt;96 % Reinheit), Low Endotoxin (&lt;1 EU\/mg), fetts\u00e4urefrei (FAF)<\/li>\n<li>Wirkstoffbindung: BSA bindet viele Wirkstoffe anders als HSA \u2013 f\u00fcr humanrelevante Proteinbindungsassays im DMPK rHSA verwenden<\/li>\n<\/ul>\n<h2>Weiterlesen<\/h2>\n<ul>\n<li><a href=\"https:\/\/seamlessbio.de\/de\/ressourcen\/blog\/rhsa-vs-bsa-serum-free-cell-culture\/\">rHSA vs. BSA \u2013 was sollten Sie verwenden?<\/a><\/li>\n<li><a href=\"https:\/\/seamlessbio.de\/de\/what-is-rhsa-recombinant-human-serum-albumin\/\">Was ist rHSA?<\/a><\/li>\n<li><a href=\"https:\/\/seamlessbio.de\/de\/what-is-fatty-acid-free-bsa\/\">Was ist fetts\u00e4urefreies BSA?<\/a><\/li>\n<li><a href=\"https:\/\/seamlessbio.de\/de\/produkte\/bsa\/\">Portfolio BSA<\/a><\/li>\n<\/ul>\n<div style=\"background:#f4f6f7;border-radius:12px;padding:32px;text-align:center;margin-top:40px;\">\n<p style=\"font-size:18px;font-weight:700;color:#1a2e35;margin-bottom:12px;\">BSA \u2013 Standard, Low Endotoxin, fetts\u00e4urefrei | SeamlessBio<\/p>\n<a href=\"https:\/\/seamlessbio.de\/de\/produkte\/bsa\/\" style=\"background:#18b7b2;color:#fff;padding:12px 28px;border-radius:50px;font-size:13px;font-weight:700;text-decoration:none;\">Zum Produkt \u2192<\/a>\n&nbsp;&nbsp;\n<a href=\"https:\/\/seamlessbio.de\/de\/kontakt\/\" style=\"border:2px solid #18b7b2;color:#139b97;padding:10px 28px;border-radius:50px;font-size:13px;font-weight:700;text-decoration:none;\">Muster anfordern<\/a>\n<\/div>\n<p style=\"font-size:13px;color:#6b7f82;margin-top:32px;border-top:1px solid #d8e8e7;padding-top:16px;\">\n<em>SeamlessBio GmbH \u00b7 Passau, Deutschland \u00b7 <a href=\"mailto:info@seamlessbio.de\">info@seamlessbio.de<\/a><\/em>\n<\/p>\t\t\t\t<\/div>\n\t\t\n<\/div>\n\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Quick Definition What is BSA (Bovine Serum Albumin)?: Bovine serum albumin (BSA) is the most abundant protein in bovine blood serum (~60% of total protein), extracted from bovine plasma and purified to &gt;96% purity. It is the most widely used protein supplement in biochemistry \u2014 used as a blocking agent in ELISA, as a carrier [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-3013","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>What is BSA (Bovine Serum Albumin)? \u2014 Definition &amp; Uses<\/title>\n<meta name=\"description\" content=\"What is BSA (bovine serum albumin), what does it do in cell culture and assay buffers, and which grade do you need? 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