{"id":3266,"date":"2026-08-27T21:17:55","date_gmt":"2026-08-27T20:17:55","guid":{"rendered":"https:\/\/seamlessbio.de\/?page_id=3266"},"modified":"2026-08-27T21:54:40","modified_gmt":"2026-08-27T20:54:40","slug":"disease-state-serum-panels","status":"publish","type":"page","link":"https:\/\/seamlessbio.de\/de\/disease-state-serum-panels\/","title":{"rendered":"Disease State Serum Panels"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"3266\" class=\"elementor elementor-3266\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b318381 e-con e-atomic-element e-flexbox-base e-fadfa6d \" data-id=\"b318381\" data-element_type=\"e-flexbox\" data-e-type=\"e-flexbox\" data-interaction-id=\"b318381\" data-e-type=\"e-flexbox\" data-id=\"b318381\">\n    \t\t<div class=\"elementor-element elementor-element-f67bfb8 elementor-widget elementor-widget-html\" data-id=\"f67bfb8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<!--\nWORDPRESS PAGE \u2014 GUTENBERG \"BENUTZERDEFINIERTES HTML\" BLOCK\nSlug: disease-state-serum-panels\nSEO Title: Disease State Serum Panels \u2014 Autoimmune, Infectious, Thyroid | SeamlessBio\nMeta Description: Human disease state serum and plasma for IVD assay development \u2014 autoimmune, infectious disease, thyroid, allergy, diabetes, oncology and inflammation. EU supplier.\nFocus Keyword: disease state serum panels IVD supplier Europe\nMeta Robots: index, follow\n-->\n\n<script type=\"application\/ld+json\">\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@graph\": [\n    {\n      \"@type\": \"BreadcrumbList\",\n      \"itemListElement\": [\n        { \"@type\": \"ListItem\", \"position\": 1, \"name\": \"Home\", \"item\": \"https:\/\/seamlessbio.de\/\" },\n        { \"@type\": \"ListItem\", \"position\": 2, \"name\": \"Products\", \"item\": \"https:\/\/seamlessbio.de\/products\/\" },\n        { \"@type\": \"ListItem\", \"position\": 3, \"name\": \"Human Biomaterials & IVD\", \"item\": \"https:\/\/seamlessbio.de\/human-biomaterials-ivd\/\" },\n        { \"@type\": \"ListItem\", \"position\": 4, \"name\": \"Disease State Serum Panels\", \"item\": \"https:\/\/seamlessbio.de\/disease-state-serum-panels\/\" }\n      ]\n    },\n    {\n      \"@type\": \"Product\",\n      \"name\": \"Disease State Serum Panels\",\n      \"brand\": { \"@type\": \"Brand\", \"name\": \"SeamlessBio\" },\n      \"description\": \"Human serum and plasma from confirmed-positive donors for IVD assay development \u2014 autoimmune, infectious disease, thyroid, allergy, diabetes, oncology, inflammation and drugs of abuse.\",\n      \"offers\": { \"@type\": \"Offer\", \"url\": \"https:\/\/seamlessbio.de\/contact\/\", \"availability\": \"https:\/\/schema.org\/InStock\", \"priceCurrency\": \"EUR\" }\n    },\n    {\n      \"@type\": \"FAQPage\",\n      \"mainEntity\": [\n        {\n          \"@type\": \"Question\",\n          \"name\": \"What disease states are available?\",\n          \"acceptedAnswer\": { \"@type\": \"Answer\", \"text\": \"We supply human serum and plasma from donors with confirmed autoimmune diseases (ANA, RF, anti-CCP, SLE, Rheumatoid Arthritis, PBC, Celiac, Crohn's, MS, Myasthenia gravis), infectious diseases (HBV, HCV, HIV, CMV, EBV, HSV, syphilis, malaria, toxoplasma), thyroid diseases (anti-TPO, TRAb, Graves, Hashimoto), allergy (total IgE, specific IgE for 30+ allergens), diabetes (Type I\/II, GAD65, IAA), oncology (PSA, CA 15-3, CA 125, CEA, AFP), and drugs of abuse (CDT, EtG, PEth, amphetamine, cocaine, opiates, THC).\" }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Are the materials available as single donations or pools?\",\n          \"acceptedAnswer\": { \"@type\": \"Answer\", \"text\": \"Both. Most disease state sera are available as single donations (150\u2013850 mL per donation) and as pooled material. Pool sizes and availability depend on the analyte. Contact us with your specific requirement \u2014 we confirm availability within 48 hours.\" }\n        }\n      ]\n    }\n  ]\n}\n<\/script>\n\n<section class=\"sb-hsm-page\">\n<div class=\"sb-hsm-container\">\n\n<nav class=\"sb-hsm-bc\">\n  <a href=\"https:\/\/seamlessbio.de\/\">Home<\/a><span>\/<\/span>\n  <a href=\"https:\/\/seamlessbio.de\/products\/\">Products<\/a><span>\/<\/span>\n  <a href=\"https:\/\/seamlessbio.de\/human-biomaterials-ivd\/\">Human Biomaterials &amp; IVD<\/a><span>\/<\/span>\n  <strong>Disease State Serum Panels<\/strong>\n<\/nav>\n\n<div class=\"sb-hsm-hero\">\n  <div class=\"sb-hsm-hero-text\">\n    <span class=\"sb-hsm-eyebrow\">200+ Analytes \u00b7 Native Human Material \u00b7 EU Donor Origin<\/span>\n    <h1>Disease State Serum Panels<\/h1>\n    <p>Human serum and plasma from confirmed-positive donors \u2014 for IVD assay development, cross-reactivity testing, calibrator production and quality control. Native human biomaterial with no additives, collected under IRB-cleared ethical framework with full donor documentation.<\/p>\n    <div class=\"sb-hsm-hero-tags\">\n      <span>Autoimmune<\/span><span>Infectious Disease<\/span><span>Thyroid<\/span>\n      <span>Allergy<\/span><span>Diabetes<\/span><span>Oncology<\/span><span>Drugs of Abuse<\/span>\n    <\/div>\n    <div class=\"sb-hsm-hero-btns\">\n      <a href=\"https:\/\/seamlessbio.de\/contact\/\" class=\"sb-hsm-btn\">Request Quote<\/a>\n      <a href=\"mailto:info@seamlessbio.de?subject=Disease%20State%20Serum%20Quote\" class=\"sb-hsm-btn-outline\">info@seamlessbio.de<\/a>\n    <\/div>\n  <\/div>\n  <div class=\"sb-hsm-hero-image\">\n    <div class=\"sb-hsm-img-fallback\" style=\"display:flex;\">Disease State Serum Panels<\/div>\n  <\/div>\n<\/div>\n\n<div class=\"sb-hsm-facts\">\n  <div class=\"sb-hsm-fact\"><span class=\"sb-hsm-fact-n\">200+<\/span><span>Disease state analytes and conditions available<\/span><\/div>\n  <div class=\"sb-hsm-fact\"><span class=\"sb-hsm-fact-n\">Native<\/span><span>No additives \u2014 as identical to patient samples as possible<\/span><\/div>\n  <div class=\"sb-hsm-fact\"><span class=\"sb-hsm-fact-n\">150\u2013850 mL<\/span><span>Single donations available \u2014 pooled bulks on request<\/span><\/div>\n  <div class=\"sb-hsm-fact\"><span class=\"sb-hsm-fact-n\">ISO 13485<\/span><span>ISO 13485 &amp; ISO 9001 certified source \u2014 in.vent Diagnostica GmbH<\/span><\/div>\n<\/div>\n\n<div class=\"sb-hsm-section\">\n  <h2>Autoimmune Diseases<\/h2>\n  <p class=\"sb-hsm-intro\">For cross-reactivity testing, assay development and QC. Available as single donations (Serum OTC or Citrate Plasma) and pools.<\/p>\n  <div class=\"sb-hsm-app-grid\">\n    <div class=\"sb-hsm-app\">\n      <h3>Connective Tissue &amp; Joint<\/h3>\n      <p>ANA, anti-CCP, Rheumatoid Factor (IgA\/IgG\/IgM), dsDNA, SS-A, SS-B, Systemic Lupus Erythematosus (SLE), Rheumatoid Arthritis, Cardiolipin IgA\/IgG\/IgM, Beta-2-Glycoprotein, U1RNP<\/p>\n    <\/div>\n    <div class=\"sb-hsm-app\">\n      <h3>Liver &amp; GI<\/h3>\n      <p>AMA-M2, Primary Biliary Cholangitis (PBC), Autoimmune Hepatitis, Celiac Disease, Crohn's Disease, Ulcerative Colitis \u2014 including faecal material<\/p>\n    <\/div>\n    <div class=\"sb-hsm-app\">\n      <h3>Neurological &amp; Vasculitis<\/h3>\n      <p>Multiple Sclerosis, Myasthenia gravis, MPO Antibodies, PR3 Antibodies, ADAMTS-13, Pernicious Anemia \u2014 Citrate Plasma, 450\u2013850 mL<\/p>\n    <\/div>\n  <\/div>\n<\/div>\n\n<div class=\"sb-hsm-section\">\n  <h2>Infectious Diseases<\/h2>\n  <div class=\"sb-hsm-app-grid\">\n    <div class=\"sb-hsm-app\">\n      <h3>Viral<\/h3>\n      <p>CMV, EBV, FSME, HBV (HBsAg, Anti-HBc), HCV, HEV (IgM + PCR), HSV-1\/2, HIV-1\/2, Influenza A\/B, Measles, VZV, Yellow Fever \u2014 Citrate Plasma<\/p>\n    <\/div>\n    <div class=\"sb-hsm-app\">\n      <h3>Bacterial<\/h3>\n      <p>Bordetella pertussis, Campylobacter, Chlamydia pneumoniae &amp; trachomatis, Helicobacter pylori, Mycoplasma pneumoniae, Syphilis (Treponema pallidum)<\/p>\n    <\/div>\n    <div class=\"sb-hsm-app\">\n      <h3>Parasitic &amp; Fungal<\/h3>\n      <p>Malaria (Ab + Ag), Toxoplasma gondii (IgA\/IgG\/IgM), Echinococcus, Schistosoma, Toxocara canis, Leishmania, Candida \u2014 Citrate Plasma<\/p>\n    <\/div>\n  <\/div>\n<\/div>\n\n<div class=\"sb-hsm-section\">\n  <h2>Thyroid Diseases<\/h2>\n  <div class=\"sb-hsm-comparison\">\n    <table class=\"sb-hsm-cmp\">\n      <thead><tr><th>Analyte \/ Condition<\/th><th>Matrix<\/th><th>Levels available<\/th><\/tr><\/thead>\n      <tbody>\n        <tr><td>Anti-TPO<\/td><td>Serum OTC \/ Citrate Plasma<\/td><td>Positive \/ High positive \/ Negative<\/td><\/tr>\n        <tr><td>Anti-Tg<\/td><td>Serum OTC \/ Citrate Plasma<\/td><td>Positive \/ High positive \/ Negative<\/td><\/tr>\n        <tr><td>TRAb<\/td><td>Serum OTC \/ Citrate Plasma<\/td><td>Positive \/ High positive \/ Negative<\/td><\/tr>\n        <tr><td>TSH<\/td><td>Serum OTC<\/td><td>Decreased \/ Increased<\/td><\/tr>\n        <tr><td>fT4 \/ fT3 \/ tT4 \/ tT3<\/td><td>Serum OTC<\/td><td>Decreased \/ Increased<\/td><\/tr>\n        <tr><td>Graves' Disease \/ Hashimoto's<\/td><td>Serum OTC<\/td><td>Confirmed diagnosis<\/td><\/tr>\n        <tr><td>Hyper\/Hypothyroidism<\/td><td>Serum OTC<\/td><td>Confirmed diagnosis<\/td><\/tr>\n        <tr><td>Anti-TPO Pool 1L \/ TRAb Pool 1L<\/td><td>Citrate Plasma \/ Serum (Pool)<\/td><td>1 L pool<\/td><\/tr>\n      <\/tbody>\n    <\/table>\n  <\/div>\n<\/div>\n\n<div class=\"sb-hsm-section\">\n  <h2>Allergy \u2014 Specific IgE<\/h2>\n  <p class=\"sb-hsm-intro\">Total IgE and specific IgE for 30+ allergens \u2014 inhalation, food, insect venom, occupational.<\/p>\n  <div class=\"sb-hsm-app-grid\">\n    <div class=\"sb-hsm-app\">\n      <h3>Inhalation &amp; Environmental<\/h3>\n      <p>House dust mite (D. pteronyssinus, rDer p1, rDer p2), cat dander, dog lipocalin (rCan f1\/2), silver birch (Bet v1), timothy grass, bermuda grass, ragweed, alternaria<\/p>\n    <\/div>\n    <div class=\"sb-hsm-app\">\n      <h3>Food Allergy<\/h3>\n      <p>Peanut (Ara h2), hazel nut, sesame, wheat, cow's milk, shrimp, fish (cod), peach (Pru p3)<\/p>\n    <\/div>\n    <div class=\"sb-hsm-app\">\n      <h3>Insect Venom &amp; Other<\/h3>\n      <p>Bee venom, common wasp venom, Vespula, latex \u2014 plus total IgE positive\/high positive\/very high positive<\/p>\n    <\/div>\n  <\/div>\n<\/div>\n\n<div class=\"sb-hsm-section\">\n  <h2>Diabetes, Inflammation, Oncology &amp; Drugs of Abuse<\/h2>\n  <div class=\"sb-hsm-comparison\">\n    <table class=\"sb-hsm-cmp\">\n      <thead><tr><th>Category<\/th><th>Analytes<\/th><th>Matrix<\/th><\/tr><\/thead>\n      <tbody>\n        <tr><td>Diabetes<\/td><td>Type I\/II (Serum + Urine), GAD65, IAA, ICA, ZnT8 Antibodies<\/td><td>Serum OTC \/ Urine<\/td><\/tr>\n        <tr><td>Inflammation<\/td><td>CRP (pos\/high), Procalcitonin (PCT), Calprotectin, SAA<\/td><td>Serum \/ Citrate Plasma<\/td><\/tr>\n        <tr><td>Oncology<\/td><td>PSA, fPSA, CA 15-3, CA 125, CA 19-9, CEA, AFP, NSE \u2014 Breast, Colon, Lung, Liver Cancer<\/td><td>Serum OTC<\/td><\/tr>\n        <tr><td>Drugs of Abuse<\/td><td>CDT (pos\/high\/very high), EtG, PEth, Amphetamine, Benzodiazepines, Cocaine, Fentanyl, Opiates, THC, Tramadol<\/td><td>Serum \/ Urine<\/td><\/tr>\n      <\/tbody>\n    <\/table>\n  <\/div>\n<\/div>\n\n<div class=\"sb-hsm-section\">\n  <h2>Frequently Asked Questions<\/h2>\n  <div class=\"sb-hsm-faqs\">\n    <div class=\"sb-hsm-faq\">\n      <h3>Are the materials available at specific titres?<\/h3>\n      <p>Availability at specific titres depends on the analyte. For most autoimmune and thyroid markers, we can provide positive, high positive and negative levels. For infectious disease markers, specific viral load ranges are available for some analytes. Contact us with your titre requirement and we confirm availability within 48 hours.<\/p>\n    <\/div>\n    <div class=\"sb-hsm-faq\">\n      <h3>Can I get consecutive donations from the same donor?<\/h3>\n      <p>Yes \u2014 consecutive donations from the same donor are available for longitudinal studies or for applications requiring the same donor matrix across a series of samples. This is available for most disease categories. Lead time varies \u2014 contact us to plan your project.<\/p>\n    <\/div>\n    <div class=\"sb-hsm-faq\">\n      <h3>Are the materials suitable for IVDR cross-reactivity testing?<\/h3>\n      <p>Yes \u2014 the disease state materials are specifically used for cross-reactivity and interference testing in IVD regulatory submissions under IVDR 2017\/746. They are native human biomaterial with confirmed diagnostic results, making them directly suitable for cross-reactivity panels required in performance evaluation studies.<\/p>\n    <\/div>\n  <\/div>\n<\/div>\n\n<div class=\"sb-hsm-section\">\n  <h2>Related Products<\/h2>\n  <div class=\"sb-hsm-related\">\n    <a href=\"https:\/\/seamlessbio.de\/ivdr-class-d-sample-sets\/\" class=\"sb-hsm-rel\">\n      <h3>IVDR Class D Sample Sets<\/h3>\n      <p>HBV, HCV, HIV compliance panels per CTS 2009\/108\/EC \u2014 for Class D IVD submissions.<\/p>\n    <\/a>\n    <a href=\"https:\/\/seamlessbio.de\/human-quality-controls-standard-materials\/\" class=\"sb-hsm-rel\">\n      <h3>Quality Controls &amp; Standards<\/h3>\n      <p>Native human-origin IQC and EQA controls for laboratory quality management.<\/p>\n    <\/a>\n    <a href=\"https:\/\/seamlessbio.de\/what-is-disease-state-serum\/\" class=\"sb-hsm-rel\">\n      <h3>What is Disease State Serum?<\/h3>\n      <p>Definition, applications and when you need it for IVD development.<\/p>\n    <\/a>\n    <a href=\"https:\/\/seamlessbio.de\/fertility-pregnancy-serum-materials\/\" class=\"sb-hsm-rel\">\n      <h3>Fertility &amp; Pregnancy Materials<\/h3>\n      <p>hCG, AMH, FSH, LH, trimester pools \u2014 for IVD assay development.<\/p>\n    <\/a>\n  <\/div>\n<\/div>\n\n<div class=\"sb-hsm-cta\">\n  <h2>Request Disease State Serum \u2014 Quote<\/h2>\n  <p>Tell us the analyte, titre range, matrix and volume \u2014 we respond within 48 hours with availability and pricing.<\/p>\n  <div class=\"sb-hsm-cta-btns\">\n    <a href=\"https:\/\/seamlessbio.de\/contact\/\" class=\"sb-hsm-btn-w\">Contact Us<\/a>\n    <a href=\"mailto:info@seamlessbio.de?subject=Disease%20State%20Serum%20Quote\" class=\"sb-hsm-btn-o\">info@seamlessbio.de<\/a>\n  <\/div>\n  <p class=\"sb-hsm-ruo\">For research use only unless stated otherwise.<\/p>\n<\/div>\n\n<\/div>\n<\/section>\n\n<style>\n.sb-hsm-page,.sb-hsm-page *,.sb-hsm-page *::before,.sb-hsm-page 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