{"id":584,"date":"2026-05-14T15:54:59","date_gmt":"2026-05-14T14:54:59","guid":{"rendered":"http:\/\/seamlessbio.de\/?page_id=584"},"modified":"2026-06-21T12:31:06","modified_gmt":"2026-06-21T11:31:06","slug":"fbs-heat-inactivated","status":"publish","type":"page","link":"https:\/\/seamlessbio.de\/de\/fbs-heat-inactivated\/","title":{"rendered":"FBS, hitzeinaktiviert"},"content":{"rendered":"
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\n Startseite<\/a>\n \/<\/span>\n Rinderserum aus F\u00f6ten<\/a>\n \/<\/span>\n FBS, hitzeinaktiviert<\/strong>\n <\/div>\n\n
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\n SeamlessBio \u2013 F\u00f6tales Rinderserum<\/span>\n

FBS, hitzeinaktiviert<\/h1>\n

\n South American-origin fetal bovine serum, processed and quality-controlled in Germany, heat-inactivated at 56\u00b0C to denature\n complement proteins \u2014 for immunological assays, sensitive cell lines\n and applications where complement activity must be eliminated.\n <\/p>\n

\n Informationen anfordern<\/a>\n Im Shop ansehen<\/a>\n <\/div>\n <\/div>\n
\n \"FBS\n
Platzhalter f\u00fcr Produktbild<\/div>\n <\/div>\n <\/div>\n\n
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\n 01<\/span>\n

Complement-Inactivated<\/h3>\n

\n Heat-treated at 56\u00b0C for 30 minutes to denature complement proteins\n and reduce non-specific immune interference.\n <\/p>\n <\/div>\n\n

\n 02<\/span>\n

Consistent Heat Treatment<\/h3>\n

\n Standardised, validated heat-inactivation process for batch-to-batch\n consistency in sensitive assay conditions.\n <\/p>\n <\/div>\n\n

\n 03<\/span>\n

Batch Documentation<\/h3>\n

\n CoA, CoO and TSE\/BSE statement available with every shipment,\n confirming heat-inactivation status.\n <\/p>\n <\/div>\n\n

\n 04<\/span>\n

Cold-Chain Delivery<\/h3>\n

\n Temperature-controlled shipment across the EU and UK, with no\n minimum order quantity.\n <\/p>\n <\/div>\n\n <\/div>\n\n

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Why heat inactivation matters for immunological work<\/h2>\n

\n Fetal bovine serum naturally contains complement proteins \u2014 a group\n of heat-sensitive serum proteins that can lyse certain cell types,\n interfere with antibody-antigen interactions, and produce\n non-specific background activity in immunological and virological\n assays.\n <\/p>\n

\n Heat inactivation denatures these complement proteins through a\n controlled 56\u00b0C treatment, eliminating complement-mediated\n interference while preserving the growth-supporting nutrients,\n hormones and growth factors that make FBS effective for cell\n culture. This makes heat-inactivated FBS the standard choice\n wherever complement activity would otherwise confound results.\n <\/p>\n

\n It is worth noting that heat inactivation provides no additional\n benefit for routine cell culture that does not involve complement-\n sensitive assays \u2014 for general expansion work, standard or\n low-endotoxin FBS is typically sufficient and more cost-effective.\n <\/p>\n <\/div>\n\n

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Typical applications<\/h3>\n