{"id":593,"date":"2026-05-14T15:54:59","date_gmt":"2026-05-14T14:54:59","guid":{"rendered":"http:\/\/seamlessbio.de\/?page_id=593"},"modified":"2026-06-21T14:44:36","modified_gmt":"2026-06-21T13:44:36","slug":"human-serum-otc-type-ab-male","status":"publish","type":"page","link":"https:\/\/seamlessbio.de\/de\/human-serum-otc-type-ab-male\/","title":{"rendered":"Menschliches Serum, OTC, Typ AB, m\u00e4nnlich"},"content":{"rendered":"
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\n Startseite<\/a>\n \/<\/span>\n Human Sera & Plasma<\/a>\n \/<\/span>\n Menschliches Serum, OTC, Typ AB, m\u00e4nnlich<\/strong>\n <\/div>\n\n
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\n SeamlessBio \u2014 Human Sera & Plasma<\/span>\n

Menschliches Serum, OTC, Typ AB, m\u00e4nnlich<\/h1>\n

\n EU and US-origin, off-the-clot, Type AB, male-donor human serum \u2014\n the reference grade for CAR-T and NK cell expansion, MSC\n manufacturing and other xeno-free ATMP workflows.\n <\/p>\n

\n Informationen anfordern<\/a>\n Im Shop ansehen<\/a>\n <\/div>\n <\/div>\n
\n \"Human\n
Platzhalter f\u00fcr Produktbild<\/div>\n <\/div>\n <\/div>\n\n
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\n 01<\/span>\n

Off-the-Clot Processing<\/h3>\n

\n Full native growth factor spectrum \u2014 PDGF, EGF, TGF-\u03b2, IGF-1 \u2014\n released through natural platelet degranulation.\n <\/p>\n <\/div>\n\n

\n 02<\/span>\n

Type AB, Male-Only Donors<\/h3>\n

\n No anti-A\/B antibodies and no TRALI risk from female donors,\n with reduced hormonal lot-to-lot variability.\n <\/p>\n <\/div>\n\n

\n 03<\/span>\n

Xeno-Free, ATMP-Aligned<\/h3>\n

\n Human-matched serum supporting Ph. Eur. 5.2.12 and EMA\/410\/01\n ancillary material guidance for cell therapy manufacturing.\n <\/p>\n <\/div>\n\n

\n 04<\/span>\n

Customisable & No MOQ<\/h3>\n

\n Donor age on request, bottle or bag packaging, from evaluation\n volumes to bulk supply.\n <\/p>\n <\/div>\n\n <\/div>\n\n

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The reference grade for cell therapy expansion<\/h2>\n

\n Human Serum OTC Type AB Male combines three properties that\n matter most for cell therapy and ATMP manufacturing: it is\n human-derived (eliminating xenogenic immune responses seen with\n bovine serum), Type AB (no anti-A\/B antibodies, making it\n compatible across donor and patient blood types), and sourced\n exclusively from male donors (removing the TRALI \u2014 transfusion-\n related acute lung injury \u2014 risk associated with female-donor\n plasma products, and reducing hormonal cycle-related variability).\n <\/p>\n

\n The off-the-clot (OTC) processing method allows platelets to\n degranulate naturally during clotting, releasing a full native\n spectrum of growth factors \u2014 including PDGF, EGF, TGF-\u03b2 and\n IGF-1 \u2014 that support robust expansion of T cells, NK cells and\n mesenchymal stromal cells.\n <\/p>\n

\n For applications where bovine-derived FBS introduces regulatory\n complications, this grade is generally the most direct\n substitute \u2014 see our FBS vs. Human Serum comparison<\/a>\n for the full regulatory and immunological context.\n <\/p>\n <\/div>\n\n

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Typical applications<\/h3>\n