{"id":3557,"date":"2026-09-16T12:09:58","date_gmt":"2026-09-16T11:09:58","guid":{"rendered":"https:\/\/seamlessbio.de\/produkt\/rocker-cell-culture-bags-customized-single-use-bioprocess-bags\/"},"modified":"2026-09-22T11:44:58","modified_gmt":"2026-09-22T10:44:58","slug":"rocker-cell-culture-bags-customized-single-use-bioprocess-bags","status":"publish","type":"product","link":"https:\/\/seamlessbio.de\/de\/product\/rocker-cell-culture-bags-customized-single-use-bioprocess-bags\/","title":{"rendered":"Rocker Cell Culture Bags \u2013 Customized Single-Use Bioprocess Bags"},"content":{"rendered":"<style>\n.sb-pd{font-family:-apple-system,BlinkMacSystemFont,\"Segoe UI\",Roboto,sans-serif;max-width:100%;color:#202020;line-height:1.75}\n.sb-pd .def{background:#e9fbfa;border-left:4px solid #18b7b2;border-radius:0 10px 10px 0;padding:16px 20px;margin:0 0 28px}\n.sb-pd .def .lb{font-size:11px;font-weight:800;text-transform:uppercase;letter-spacing:.09em;color:#139b97;display:block;margin-bottom:5px}\n.sb-pd .def p{font-size:15px;margin:0;font-weight:500}\n.sb-pd h2{font-size:21px;font-weight:800;margin:32px 0 10px;color:#111;border-bottom:2px solid #e2eceb;padding-bottom:7px}\n.sb-pd h3{font-size:15px;font-weight:700;color:#18b7b2;margin:18px 0 5px}\n.sb-pd p{margin:0 0 12px;font-size:15px}\n.sb-pd ul{margin:0 0 12px;padding-left:20px}\n.sb-pd li{margin-bottom:6px;font-size:14px}\n.sb-pd .cards{display:grid;grid-template-columns:repeat(3,1fr);gap:12px;margin:14px 0 20px}\n.sb-pd .card{background:#f1faf9;border:1px solid #daf3f2;border-top:3px solid #18b7b2;border-radius:0 0 10px 10px;padding:14px}\n.sb-pd .card h3{margin:0 0 5px;font-size:13px;color:#111}\n.sb-pd .card p{margin:0;font-size:12px;color:#5b6b71}\n.sb-pd table{width:100%;border-collapse:collapse;font-size:14px;margin:14px 0 20px}\n.sb-pd th{background:#18b7b2;color:#fff;text-align:left;padding:9px 13px;font-weight:700}\n.sb-pd td{padding:9px 13px;border-bottom:1px solid #e2eceb;vertical-align:top}\n.sb-pd tr:nth-child(even) td{background:#f8fffe}\n.sb-pd td:first-child{font-weight:600;color:#111;width:35%}\n.sb-pd .qa{background:#f8fffe;border:1px solid #daf3f2;border-radius:8px;padding:14px 16px;margin:10px 0}\n.sb-pd .qa .q{font-weight:700;color:#111;margin:0 0 5px;font-size:14px}\n.sb-pd .qa .a{margin:0;font-size:13px;color:#444}\n.sb-pd .cta{background:linear-gradient(135deg,#e4f6f5,#f4fbfb);border:1px solid rgba(24,183,178,.2);border-radius:12px;padding:20px;margin-top:28px;text-align:center}\n.sb-pd .cta h3{margin:0 0 7px;font-size:17px;color:#111}\n.sb-pd .cta p{margin:0 0 14px;font-size:13px;color:#5b6b71}\n.sb-pd .btn{display:inline-block;background:#18b7b2;color:#fff!important;padding:9px 20px;border-radius:7px;font-weight:700;font-size:13px;text-decoration:none!important;margin:0 4px}\n.sb-pd .btn-o{display:inline-block;border:2px solid #18b7b2;color:#18b7b2!important;padding:7px 20px;border-radius:7px;font-weight:700;font-size:13px;text-decoration:none!important;margin:0 4px}\n.sb-pd a{color:#18b7b2;font-weight:600}\n@media(max-width:600px){.sb-pd .cards{grid-template-columns:1fr}}\n<\/style>\n<div class=\"sb-pd\">\n<h2>Product Overview<\/h2>\n<p><strong>SeamlessBio Single-Use Rocker Bags<\/strong> are film-based cultivation bags engineered specifically for rocking and wave-style bioreactor platforms (such as GE WAVE\u2122, Sartorius BIOSTAT RM\u2122, Thermo Fisher HyWave\u2122, and Applikon). The gentle, low-shear rocking motion provides oxygen and CO\u2082 exchange without mechanical impeller agitation \u2014 the preferred cultivation format for shear-sensitive mammalian cell lines, microcarrier-based adherent cultures, stem cell expansion, and seed train workflows. Available in <strong>10 L, 20 L, and 50 L<\/strong> working volumes, gamma irradiated to SAL 10\u207b\u2076, with fully customisable port configurations. Manufactured under ISO Class 7 cleanroom conditions with complete GMP documentation.<\/p>\n<h2>Available Formats<\/h2>\n<table>\n<thead>\n<tr>\n<th>Format<\/th>\n<th>Working Volume<\/th>\n<th>Primary Use<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><a href=\"https:\/\/seamlessbio.de\/de\/rocker-tasche-10-l\/\"><strong>10-Liter-Rocker-Tasche<\/strong><\/a><\/td>\n<td>10 l<\/td>\n<td>Process development, clone selection, small-scale rocking bioreactor work<\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/seamlessbio.de\/de\/rocker-tasche-20-l\/\"><strong>20-Liter-Rocker-Tasche<\/strong><\/a><\/td>\n<td>20 l<\/td>\n<td>Mid-scale seed train expansion and production workflows<\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/seamlessbio.de\/de\/rocker-tasche-50-l\/\"><strong>50-Liter-Rocker-Tasche<\/strong><\/a><\/td>\n<td>50 l<\/td>\n<td>Scale-up campaigns and higher-volume rocking bioreactor production<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Why Rocking Bioreactor Bags vs. Stirred-Tank Systems?<\/h2>\n<table>\n<thead>\n<tr>\n<th>Parameter<\/th>\n<th>Rocking Bag Bioreactor<\/th>\n<th>Stirred-Tank Bioreactor<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Agitation mechanism<\/td>\n<td>Oscillating rocking motion \u2014 wave-induced mixing<\/td>\n<td>Mechanical impeller rotation<\/td>\n<\/tr>\n<tr>\n<td>Scherbeanspruchung<\/td>\n<td>Very low \u2014 suitable for shear-sensitive cells<\/td>\n<td>Higher \u2014 can damage fragile cell types<\/td>\n<\/tr>\n<tr>\n<td>Gas exchange<\/td>\n<td>Surface aeration + headspace CO\u2082\/O\u2082 exchange<\/td>\n<td>Sparger-based \u2014 bubble-induced shear risk<\/td>\n<\/tr>\n<tr>\n<td>Microcarrier culture<\/td>\n<td>Excellent \u2014 gentle suspension of carrier beads<\/td>\n<td>Possible but requires careful impeller selection<\/td>\n<\/tr>\n<tr>\n<td>Cleaning &amp; validation<\/td>\n<td>None required \u2014 single use, gamma-irradiated<\/td>\n<td>Full CIP\/SIP cycles required<\/td>\n<\/tr>\n<tr>\n<td>Scale-up flexibility<\/td>\n<td>10 L \u2192 20 L \u2192 50 L without platform change<\/td>\n<td>Requires new vessel and re-validation<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Anwendungen<\/h2>\n<table>\n<thead>\n<tr>\n<th>Anwendung<\/th>\n<th>Description<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Scherkraftempfindliche S\u00e4ugetierzellkultur<\/strong><\/td>\n<td>CHO, HEK293, Vero, and BHK21 cell lines where impeller agitation causes unacceptable cell damage or productivity loss<\/td>\n<\/tr>\n<tr>\n<td><strong>Microcarrier-based adherent culture<\/strong><\/td>\n<td>Scale-up of adherent cells (e.g. Vero for vaccine production, MSCs) on Cytodex or similar microcarriers \u2014 rocking motion provides gentle bead suspension without excessive shear<\/td>\n<\/tr>\n<tr>\n<td><strong>Stem cell &amp; primary cell expansion<\/strong><\/td>\n<td>iPSC, MSC, and primary cell types with high shear sensitivity \u2014 rocking platforms maintain viability and phenotype across passages<\/td>\n<\/tr>\n<tr>\n<td><strong>Impfstoffherstellung<\/strong><\/td>\n<td>Virus propagation on rocking bioreactor platforms using Vero or MDCK substrates \u2014 established manufacturing format for influenza, rabies, and viral vector vaccines<\/td>\n<\/tr>\n<tr>\n<td><strong>Seed train &amp; process development<\/strong><\/td>\n<td>N-1 seed train steps, DOE screening, and clone selection at 10\u201350 L scale before transfer to stirred-tank production vessels<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Key Benefits<\/h2>\n<div class=\"cards\">\n<div class=\"card\">\n<h3>Drop-In Platform Compatibility<\/h3>\n<p>Compatible with GE WAVE\u2122, Sartorius BIOSTAT RM\u2122, Thermo Fisher HyWave\u2122, and Applikon rocking platforms \u2014 fits existing hardware without modification.<\/p>\n<\/div>\n<div class=\"card\">\n<h3>Vollst\u00e4ndige Dokumentation<\/h3>\n<p>Batch-specific CoA, CoO, and Leachables\/Extractables\/Tox Validation Guide \u2014 from ISO Class 7 GMP manufacturing facilities. Additional regulatory documents on request.<\/p>\n<\/div>\n<div class=\"card\">\n<h3>EU &amp; Swiss Supply<\/h3>\n<p>Stocked in Germany \u2014 fast cold-chain delivery across EU, UK and Switzerland. Custom port configurations available with short lead times.<\/p>\n<\/div>\n<\/div>\n<h2>H\u00e4ufig gestellte Fragen<\/h2>\n<div class=\"qa\">\n<p class=\"q\">Which rocking bioreactor platforms are SeamlessBio rocker bags compatible with?<\/p>\n<p class=\"a\">SeamlessBio rocker bags are engineered for compatibility with the major rocking\/wave bioreactor platforms in use across the EU and globally, including GE Healthcare WAVE\u2122 (now Cytiva), Sartorius BIOSTAT RM\u2122, Thermo Fisher HyWave\u2122, and Applikon rocking systems. The bag dimensions and port configurations are designed to match standard platform requirements. If you are using a less common platform, contact our team with the equipment model and required bag format \u2014 we can advise on compatibility or produce a custom-dimensioned bag.<\/p>\n<\/div>\n<div class=\"qa\">\n<p class=\"q\">Why are rocking bioreactor bags preferred for shear-sensitive cell lines?<\/p>\n<p class=\"a\">Rocking bioreactor bags mix and oxygenate the culture by oscillating the bag on a rocking tray, creating a wave motion that distributes cells and nutrients without mechanical impeller agitation. This eliminates the high local shear zones that impeller tips create in stirred-tank systems, which can lyse fragile cells or trigger stress responses that reduce productivity. The format is particularly well-established for primary cells, iPSCs, MSCs, microcarrier-based adherent cultures, and virus production on sensitive substrates such as Vero cells.<\/p>\n<\/div>\n<div class=\"qa\">\n<p class=\"q\">Can rocker bags be used for microcarrier-based adherent cell culture?<\/p>\n<p class=\"a\">Yes \u2014 this is one of the primary applications. The gentle rocking motion provides sufficient agitation to keep microcarrier beads (e.g. Cytodex 1, Cytodex 3, or similar) in suspension without the shear forces that cause bead-to-bead collision damage or cell detachment. Working volumes of 10\u201350 L are well-suited for scale-up from static flask or spinner flask culture to rocking bioreactor production. The 20 L and 50 L formats are frequently used for Vero-based virus production on microcarriers at clinical and commercial scale.<\/p>\n<\/div>\n<div class=\"qa\">\n<p class=\"q\">Are custom port configurations available?<\/p>\n<p class=\"a\">Yes \u2014 all SeamlessBio rocker bags are available with customised port configurations. Standard configurations include inlet\/outlet ports, a sparger tube for gas delivery, and a sampling port. Additional ports (vent filters, pH\/DO sensor ports, harvest ports, Luer Lock sampling), alternative connector types (MPC, Luer Lock, AseptiQuik\u00ae), and custom tubing materials (TPE or platinum-cured silicone) can be specified on order. Contact our team with your process requirements and bioreactor platform model for a configuration recommendation.<\/p>\n<\/div>\n<div class=\"qa\">\n<p class=\"q\">What documentation is provided for GMP and regulatory compliance?<\/p>\n<p class=\"a\">Every batch ships with a batch-specific Certificate of Analysis (CoA) and Certificate of Origin (CoO). A Leachables, Extractables &amp; Toxicological (Tox) Validation Guide is available on request, along with USP Class VI compliance statements, ADCF declarations, and irradiation certificates (ISO 11137). All bags are manufactured in ISO Class 7 cleanroom conditions and gamma irradiated to SAL 10\u207b\u2076. Documentation packages support IND, CTA, and MAA submissions referencing single-use bag components.<\/p>\n<\/div>\n<div class=\"cta\">\n<h3>Request a Quote or Custom Configuration<\/h3>\n<p>48h response \u00b7 EU &amp; Swiss Supply \u00b7 Custom port configurations \u00b7 Full GMP documentation<\/p>\n<p>  <a href=\"https:\/\/seamlessbio.de\/de\/request-quote\/\" class=\"btn\">Request Quote \u2192<\/a><br \/>\n  <a href=\"https:\/\/seamlessbio.de\/de\/produkte\/single-use-bioprocessing\/\" class=\"btn-o\">Bioprocessing Portfolio \u2192<\/a>\n<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Rocker Cell Culture Bags \u2013 Customized Single-Use Bioprocess Bags. Available in 1L, 2L, 5L, 10L, 20L. Price on request \u2014 contact our team for availability, batch documentation and delivery. <\/p>\n<div style='margin-top:12px'><a href='https:\/\/seamlessbio.de\/de\/sammelreservierung\/' style='display:block;background:#fff;border:2px solid #18b7b2;color:#18b7b2;padding:10px 24px;border-radius:8px;font-weight:700;font-size:14px;text-decoration:none;text-align:center;'>Test Sample &amp; Batch Reservation \u2192<\/a><\/div>","protected":false},"featured_media":3732,"template":"","meta":{"_eb_attr":""},"product_brand":[],"product_cat":[97],"product_tag":[98,99,100,101,57,102,103,104,105,106,107,108,109,110],"class_list":["post-3557","product","type-product","status-publish","has-post-thumbnail","product_cat-single-use-bioprocessing","product_tag-atmp","product_tag-biopharmaceutical","product_tag-bioprocessing","product_tag-bioprocssing","product_tag-biotechnology","product_tag-car-t","product_tag-cell-culture-bag","product_tag-corning-alternative","product_tag-customized","product_tag-disposable-bag","product_tag-rocker-bag","product_tag-rocking-bioreactor","product_tag-single-use-bag","product_tag-single-use-bioreactor","first","instock","taxable","shipping-taxable","product-type-simple"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Single-Use Rocker Bags 10\u201350 L | Wave Bioreactor | cGMP<\/title>\n<meta name=\"description\" content=\"SeamlessBio single-use rocker bags for wave and rocking bioreactor platforms \u2014 10 L, 20 L, 50 L. 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