{"id":9748,"date":"2026-10-26T08:22:43","date_gmt":"2026-10-26T07:22:43","guid":{"rendered":"https:\/\/seamlessbio.de\/?post_type=product&#038;p=9748"},"modified":"2026-10-29T08:57:30","modified_gmt":"2026-10-29T07:57:30","slug":"humanes-thrombozytenlysat-hpl-gmp-eu","status":"publish","type":"product","link":"https:\/\/seamlessbio.de\/de\/product\/human-platelet-lysate-hpl-gmp-eu-origin\/","title":{"rendered":"Humanes Thrombozytenlysat (hPL) \u2013 Research- &amp; GMP-Qualit\u00e4t, EU-Herkunft"},"content":{"rendered":"<div class=\"sb-pd\">\n<div class=\"def\"><span class=\"lb\">Auf einen Blick<\/span><\/p>\n<p>Humanes Thrombozytenlysat (hPL) aus regulierten EU-Thrombozytenspenden \u2013 der xenofreie Ersatz f\u00fcr f\u00f6tales K\u00e4lberserum in MSC- und Prim\u00e4rzellkultur, ATMP-Herstellung und 3D-Kultur. Research-, GMP- und GMP-Clinical-Qualit\u00e4t.<\/p>\n<\/div>\n<h2>Produkt\u00fcbersicht<\/h2>\n<p>FKS bringt undefinierte tierische Bestandteile, Chargenschwankungen und regulatorische Risiken in die Herstellung neuartiger Therapien. hPL ist humanen Ursprungs und xenofrei und liefert native Wachstumsfaktoren aus lysierten Thrombozyten \u2013 PDGF-AB, EGF, TGF-\u03b21, VEGF, bFGF und IGF-1 \u2013 f\u00fcr eine robuste MSC-Proliferation ohne rekombinante Zusatzcocktails.<\/p>\n<h2>Qualit\u00e4tsstufen<\/h2>\n<table>\n<thead>\n<tr>\n<th>Qualit\u00e4t<\/th>\n<th>Format<\/th>\n<th>Verwendung<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Forschung<\/td>\n<td>Standard \u00b7 fibrinogenabgereichert<\/td>\n<td>Akademische Forschung, Assayentwicklung<\/td>\n<\/tr>\n<tr>\n<td>GMP<\/td>\n<td>Fibrinogenabgereichert<\/td>\n<td>Pr\u00e4klinik und Prozessentwicklung f\u00fcr die Zelltherapie<\/td>\n<\/tr>\n<tr>\n<td>GMP-Clinical<\/td>\n<td>Fibrinogenabgereichert, virusinaktiviert<\/td>\n<td>ATMP-Herstellung, klinische Zelltherapie<\/td>\n<\/tr>\n<tr>\n<td>3D-Matrix-Kit<\/td>\n<td>Fibrinogen-Hydrogel aus hPL<\/td>\n<td>3D-Kultur, Bioprinting, Organoide<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Anwendungen<\/h2>\n<ul>\n<li>MSC-Expansion \u2013 Knochenmark, Fettgewebe, Nabelschnur<\/li>\n<li>Prozessentwicklung f\u00fcr allogene Zelltherapien<\/li>\n<li>GMP-Herstellung MSC-basierter ATMP<\/li>\n<li>Prim\u00e4rzellkultur \u2013 Fibroblasten, Endothelzellen, Keratinozyten<\/li>\n<li>Organoid- und Organ-on-a-Chip-Kultur<\/li>\n<li>FBS-Ersatz beim Prozesstransfer in die klinische Phase<\/li>\n<\/ul>\n<h2>Technische Daten<\/h2>\n<ul>\n<li>Herkunft: EU-Thrombozytenkonzentrate gesunder Spender, gewonnen nach europ\u00e4ischen Richtlinien<\/li>\n<li>Fibrinogen-depletierte Formate: gerinnselfrei und heparinfrei \u2013 kein Antikoagulans in der Zellkultur oder Herstellung n\u00f6tig<\/li>\n<li>GMP-Clinical-Qualit\u00e4t: validierte Virusinaktivierung<\/li>\n<li>Dokumentation: CoA, SDB; GMP-Qualit\u00e4ten mit R\u00fcckverfolgbarkeits- und Chargenfreigabedokumenten<\/li>\n<li>Regulatorische Ausrichtung: EMA-ATMP-Verordnung EG 1394\/2007, EU-GMP Anhang 2<\/li>\n<li>50 mL, 100 mL, 500 mL, 250-mL-Blutbeutel<\/li>\n<li>Mindestbestellmenge: keine \u00b7 kostenlose Testmuster<\/li>\n<\/ul>\n<h2>GMP-Qualit\u00e4t, fibrinogen-depletiert \u2013 technische Daten<\/h2>\n<table>\n<tr>\n<th>Parameter<\/th>\n<th>Spezifikation<\/th>\n<\/tr>\n<tr>\n<td>Format<\/td>\n<td>Fibrinogen-depletiertes, heparinfreies hPL; gerinnselfrei, gebrauchsfertig<\/td>\n<\/tr>\n<tr>\n<td>Tierische Bestandteile<\/td>\n<td>Keine \u2013 xenofrei, humanen Ursprungs<\/td>\n<\/tr>\n<tr>\n<td>Herkunft und R\u00fcckverfolgbarkeit<\/td>\n<td>Thrombozytenkonzentrate aus der EU; Rohstoff-R\u00fcckverfolgbarkeit \u00fcber 30 Jahre<\/td>\n<\/tr>\n<tr>\n<td>Packungsgr\u00f6\u00dfen<\/td>\n<td>50 ml, 100 ml, 500 ml<\/td>\n<\/tr>\n<tr>\n<td>Lagerung<\/td>\n<td>Tiefgefroren bei \u221240 \u00b0C bis \u221220 \u00b0C<\/td>\n<\/tr>\n<tr>\n<td>Haltbarkeit<\/td>\n<td>2 Jahre ab Herstellungsdatum, tiefgefroren in der Originalflasche<\/td>\n<\/tr>\n<tr>\n<td>Arbeitskonzentration<\/td>\n<td>1\u201310 % (v\/v) in Basalmedium (z. B. MEM \u03b1, DMEM); Optimum f\u00fcr Ihren Zelltyp bestimmen<\/td>\n<\/tr>\n<tr>\n<td>Nach dem Auftauen<\/td>\n<td>Aufgetautes hPL und Komplettmedium bis zu 7 Tage bei 4 \u00b0C stabil<\/td>\n<\/tr>\n<tr>\n<td>Sterilit\u00e4t<\/td>\n<td>Aseptisch hergestellt; mikrobielle Kulturen negativ getestet; QC-Pr\u00fcfung in einem zertifizierten Pr\u00fcflabor<\/td>\n<\/tr>\n<tr>\n<td>Dokumentation<\/td>\n<td>Analysenzertifikat (CoA) und Sicherheitsdatenblatt<\/td>\n<\/tr>\n<tr>\n<td>Bestimmungsgem\u00e4\u00dfer Verwendungszweck<\/td>\n<td>Herstellungszwecke; nicht zur direkten Anwendung an Mensch oder Tier oder zur therapeutischen Verwendung<\/td>\n<\/tr>\n<\/table>\n<h2>Handhabung<\/h2>\n<ul>\n<li>Vollst\u00e4ndig im 37 \u00b0C-Wasserbad auftauen oder, falls kein Wasserbad verf\u00fcgbar ist, bei Raumtemperatur.<\/li>\n<li>Nach dem Auftauen k\u00f6nnen Partikel oder Tr\u00fcbungen auftreten; sie beeintr\u00e4chtigen die Zellkultur nicht. Bei Bedarf das unverd\u00fcnnte hPL 3\u20135 Minuten bei 3.400 \u00d7 g zentrifugieren.<\/li>\n<li>hPL dem Basalmedium zugeben \u2013 kein Heparin n\u00f6tig.<\/li>\n<li>Nicht ben\u00f6tigtes hPL nach dem Auftauen aliquotieren und wieder einfrieren; wiederholte Einfrier-Auftau-Zyklen vermeiden.<\/li>\n<li>Als Material aus menschlichem Blut nach \u00fcblicher Biosicherheitspraxis handhaben.<\/li>\n<\/ul>\n<h2>Die wichtigsten Vorteile<\/h2>\n<div class=\"cards\">\n<div class=\"card\">\n<h3>Sammelreservierung<\/h3>\n<p>Reservieren Sie Ihre Charge bis zu 36 Monate mit kostenloser Lagerung im EU-K\u00fchllager \u2013 ohne Vorauszahlung.<\/p>\n<\/div>\n<div class=\"card\">\n<h3>Vollst\u00e4ndige Dokumentation<\/h3>\n<p>CoA und SDB zu jeder Charge; R\u00fcckverfolgbarkeitsdokumentation f\u00fcr GMP-Qualit\u00e4ten.<\/p>\n<\/div>\n<div class=\"card\">\n<h3>Lieferung EU &amp; Schweiz<\/h3>\n<p>Versand aus dem EU-Lager; Kunden in der Schweiz beliefert die Seamless Bio GmbH in CHF.<\/p>\n<\/div>\n<\/div>\n<h2>H\u00e4ufig gestellte Fragen<\/h2>\n<div class=\"qa\">\n<p class=\"q\">Warum FKS durch hPL ersetzen?<\/p>\n<p class=\"a\">hPL ist xenofrei und humanen Ursprungs, beseitigt das Risiko bovinen Ursprungs und ist nach EMA-Leitlinien die bevorzugte FKS-Alternative f\u00fcr die ATMP-Herstellung.<\/p>\n<\/div>\n<div class=\"qa\">\n<p class=\"q\">Was bedeutet fibrinogenabgereichert?<\/p>\n<p class=\"a\">Standard-hPL ben\u00f6tigt Heparin, um Gerinnung zu verhindern. Bei fibrinogenabgereichertem hPL ist diese Fraktion entfernt \u2013 kein Heparin, einfachere Handhabung, weniger Variabilit\u00e4t.<\/p>\n<\/div>\n<div class=\"qa\">\n<p class=\"q\">Welche Qualit\u00e4t brauche ich?<\/p>\n<p class=\"a\">Research-Qualit\u00e4t f\u00fcr die akademische Forschung, GMP-Qualit\u00e4t f\u00fcr die Prozessentwicklung, GMP-Clinical-Qualit\u00e4t (virusinaktiviert) f\u00fcr die klinische ATMP-Herstellung.<\/p>\n<\/div>\n<div class=\"qa\">\n<p class=\"q\">Kann ich eine Produktionscharge reservieren?<\/p>\n<p class=\"a\">Ja \u2013 Chargenreservierung f\u00fcr Produktionskampagnen bis zu 36 Monate, ohne Vorauszahlung.<\/p>\n<\/div>\n<div class=\"cta\">\n<h3>Angebot oder Muster anfordern<\/h3>\n<p>Nennen Sie uns Qualit\u00e4t, Format und Menge \u2013 wir senden Dokumentation und ein kostenloses Testmuster.<\/p>\n<p><a href=\"https:\/\/seamlessbio.de\/de\/request-quote\/\">Angebot anfordern<\/a> \u00b7 <a href=\"mailto:info@seamlessbio.de\">info@seamlessbio.de<\/a><\/p>\n<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<div class=\"sb-aeo-box\">\n<p>Humanes Thrombozytenlysat (hPL) aus der EU \u2013 xenofreie FKS-Alternative f\u00fcr MSC-Expansion und Zelltherapie. Research-, GMP- und GMP-Clinical-Qualit\u00e4t, fibrinogenabgereicherte und virusinaktivierte Formate. Kostenlose Testmuster. Preis auf Anfrage.<\/p>\n<\/div>","protected":false},"featured_media":0,"template":"","meta":{"_templately_pack_id":"","_templately_imported_at":"","_templately_source":"","_templately_import_session_id":""},"product_brand":[],"product_cat":[20],"product_tag":[],"class_list":["post-9748","product","type-product","status-publish","product_cat-human-sera","first","instock","taxable","shipping-taxable","product-type-simple"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Buy Human Platelet Lysate (hPL) | GMP, EU | SeamlessBio<\/title>\n<meta name=\"description\" content=\"Buy EU human platelet lysate (hPL) \u2013 xeno-free FBS alternative for MSC and cell therapy. Research, GMP and GMP-clinical grade. 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