Human Serum & Plasma — 10 Variants

Human serum is our key long-term product — the xeno-free, physiologically relevant alternative to FBS for human primary cell culture, CAR-T manufacturing, T-cell assays and ATMP development.

• Human Serum Standard — pooled, mixed gender, mixed blood type. For immunoassay matrix and general cell culture.
• Human Serum Male — HLA alloantibody-free. For MLR, ELISPOT and antigen-specific T-cell assays.
• Human Serum Type AB Male — no anti-A/B antibodies AND no HLA alloantibodies. Standard for CAR-T expansion.
• Human Serum OTC (Off-the-Clot) — maximum growth factors (PDGF, EGF, TGF-β, FGF) from natural platelet degranulation.
• Human Serum OTC Type AB — OTC growth factors + universal blood type AB. For MSC, HSC and organoid expansion.
• Human Serum OTC AB Male — maximum growth factors + AB + HLA alloantibody-free. Premium ATMP format.
• Human Plasma — K2 EDTA or Na Citrate. Fibrinogen retained. For coagulation assays and fibrin-based matrices.
• Human Serum Delipidated — standard, IgG-free and double charcoal variants. CLSI EP7, IVD calibrators, steroid assays.
• Human Platelet Lysate (hPL) — xeno-free, GMP-compatible. The standard FBS replacement for GMP MSC expansion.
• Auto-Immune Controls — ANA, ANCA, RF disease-state serum. For IVD autoimmune assay QC.

EU and US donor centres. Processed in Germany. IVDR documentation on request. Lot reservation without prepayment.

Albumin & Proteins — BSA, HSA & rHSA

Complete albumin range across three product families, each in 4 grades for different application requirements:

• BSA Standard Grade — general cell culture blocking, ELISA and assay buffers.
• BSA Low Endotoxin — for endotoxin-sensitive applications and immunoassay development.
• BSA Fatty Acid-Free — for DMPK assay buffers, lipid binding studies and defined media.
• BSA pH 5.2 — for specific buffer formulations.
• HSA Excipient Grade — pharmacopoeial, for pharmaceutical formulations.
• HSA Diagnostic Grade — for IVD calibrator and control manufacturing. IVDR documentation available.
• HSA Cell Culture Grade — xeno-free, ISO 13485 aligned. For ATMP and cell therapy formulations.
• HSA Research Grade — cost-effective R&D use. US-origin.
• rHSA Economy — recombinant HSA, cost-effective. Yeast-expressed.
• rHSA Premium — recombinant HSA, high purity. For xeno-free defined cell culture.
• rHSA CHO-Expressed — human cell-line expressed, highest purity for clinical applications.

Cell Culture Media & Reagents

• NaivaCore — EU's first HENSM-based naive stem cell medium. Licensed from Renewal Bio Ltd. Ground-state naive hPSC culture. Three components: NaivaCore-B (basal), NaivaCore-SI ×100 (inhibitor cocktail), NaivaCore-NT ×50 (neurotrophic supplement).
• OrganoMedium — defined serum-free medium for intestinal, hepatic and neural organoid culture. Eliminates serum lot-to-lot variability.
• Serum-Free Media for HEK293 — defined SFM for HEK293 and HEK293T. AAV vector, lentiviral vector and recombinant protein production.
• Serum-Free Media for CHO — defined SFM for CHO cell culture. mAb production, recombinant protein expression and biosimilar manufacturing.
• Custom Cell Culture Media (CDMO) — bespoke serum-free and chemically defined media formulation to your cell line and regulatory requirements.
• Serum Replacement — defined serum substitute for serum-free cell culture formulations.
• Separation Solution — density gradient separation for PBMC isolation and cell separation workflows.
• Amino Acids — L-Glutamine (200 mM), L-Alanyl-L-Glutamine dipeptide (stable), NEAA 100× and custom formulations.
• Antibody & Proteins — protein supplements for serum-free media and assay development.

Single-Use Bioprocessing

• 2D Bioprocessing Bags — pillow/flat bags for media preparation, buffer storage and mixing. 150 mL to 200+ L. USP Class VI, gamma-sterilised.
• 3D Bioprocessing Bags — three-dimensional bioreactor bags for cell culture and fermentation with aeration and mixing. Multiple port configurations.
• Rocker / Wave Bags — 10L, 20L and 50L formats for rocking/wave-style bioreactor platforms.
• Tank Liners — single-use liners for existing stainless steel vessels. Eliminates CIP/SIP between batches.
• Container System — stainless steel containers (200L, 500L, 1000L) and matching dollies for single-use bag storage, transport and draining. Cleanroom-suitable, made in Germany. Sourced, configured and assembled by SeamlessBio. Custom sizes on request.
• 2D vs. 3D Selection Guide — application-specific guide: when to use 2D vs. 3D bags for media prep, storage or bioreactor applications.

DMPK & ABC Transporter Kits

Exclusive DACH distribution for Cell4Pharma (Belgium) ABC transporter vesicle kits — for IND-enabling drug interaction and transporter inhibition studies in accordance with FDA, EMA and ICH M12 guidelines.

• ABC Transporter Vesicle Kits Overview — full panel of HEK293-expressed membrane vesicle kits.
• BSEP Vesicle Kit — Bile Salt Export Pump. For hepatotoxicity and DILI risk assessment.
• BCRP Vesicle Kit — Breast Cancer Resistance Protein efflux transporter.
• P-gp Vesicle Kit — P-glycoprotein (MDR1/ABCB1). The standard IND efflux transporter assay.
• MRP1 – MRP5, MRP8 Vesicle Kits — full MRP family for multidrug resistance profiling.
• Control Vesicle Kit — empty vector control vesicles for assay validation.
• Ciptec Drug Transporter Assay Service — full GLP-compliant ABC transporter IC50 service. IND-enabling DMPK package delivery.

Services

• Serum Processing — heat inactivation (56°C/30 min), charcoal absorption (single/double), gamma irradiation (25–45 kGy), delipidation, ultra-low IgG depletion, dialysis (3.5–50 kDa MWCO) and external virus safety testing. Applied to SeamlessBio stock or customer-supplied lots.
• Batch Reservation — hold your validated FBS or human serum lot for up to 12 months, no prepayment. Call off as needed. Essential for IVD calibrator programmes and ATMP manufacturing.
• OEM & Private Label — all biological products supplied under your brand. CoA, label and documentation to your specification. NDA on request.
• CDMO — Custom Cell Culture Media — bespoke serum-free and defined media development for your cell line, process and regulatory requirements.
• Custom Human Serum Manufacturing — custom-specification human serum for distributors: donor selection, blood type, processing grade, white-label delivery. Made in Germany.
• Bioprocessing Sourcing & Assembly — stainless steel container systems (200L–1000L) sourced, configured and assembled to your specification. One point of contact, made in Germany.