Description
Product Overview
SeamlessBio Human Serum – Type AB (Male Donor) is obtained from certified donor centers in the European Union and the United States, collected under controlled and traceable conditions.
Each batch is sterile filtered at 0.2 µm, heat inactivated or gamma irradiated, ensuring the highest level of purity and biosafety for cell culture and diagnostic use.
Type AB serum is free of anti-A and anti-B antibodies, making it ideal for applications where cross-reactivity must be minimized — such as immunology, cell therapy, antibody production, and diagnostic assays.
This physiologically balanced serum provides consistent performance and reproducibility across experiments. Learn more about what Human AB Serum is and how it is used in cell culture.
Human Serum – Type AB: Quality and Applications
- Origin: EU or US (certified, traceable donor centers)
- Donor Type: Type AB (Male) – no anti-A or anti-B antibodies
- Processing:
– Heat inactivated (56 °C, 30 min)
– Gamma irradiated for viral and microbial inactivation - Filtration: 0.2 µm sterile filtered
- Fully documented and batch-tested for pH, osmolality, protein concentration, and sterility
- Standard volumes: 50 mL, 100 mL and 500 mL (custom sizes on request)
- Documentation: CoA, COO, MSDS available upon request
Applications
- Human cell culture and primary cell expansion
- Immunology and antibody development
- Diagnostic kit formulation and validation — see our Human Biomaterials & IVD portfolio
- Vaccine, cell therapy, and biomedical research
Additional Plasma Options
SeamlessBio also provides complementary plasma products:
- Human Plasma Bags – available in multiple volumes and anticoagulant options (on request)
- Disease-Specific Plasma Samples – characterized donor plasma from specific conditions, ideal for diagnostic and assay development
All materials are ethically collected, traceable, and processed under strict biosafety standards. Explore the full Human Sera, Plasma & More portfolio.
Specifications
- Filtration: 0.2 µm sterile filtered
- Processing: Heat inactivated or gamma irradiated
- Storage: –20 °C (cold-chain required)
- Documentation: CoA, COO, MSDS available
Available Formats
| Format | Size |
|---|---|
| Unit | 50 mL / Heat Inactivated |
| 100 mL / Heat Inactivated | |
| 500 mL / Heat Inactivated | |
| 50 mL / Native | |
| 50 mL / Gamma Irradiated | |
| 100 mL / Native | |
| 100 mL / Gamma Irradiated | |
| 500 mL / Native | |
| 500 mL / Gamma Irradiated |
Key Benefits
Batch Reservation
Reserve validated lots up to 36 months for reproducible long-term workflows.
Full Documentation
CoA, BSE/TSE, sterility certificate — supplied by ISO 9001 and ISO 13485 certified partner facilities. Additional documents on request.
EU & Swiss Supply
Sourced from certified EU and Swiss partner facilities — fast delivery across EU, UK and Switzerland, full documentation included.
Frequently Asked Questions
What makes Human Serum Type AB (Male) suitable for cell culture?
Type AB serum contains no anti-A or anti-B antibodies, eliminating cross-reactivity that could interfere with cells or assays. Male donor serum is preferred because it avoids hormone variability associated with female donors. Combined with 0.2 µm sterile filtration and heat inactivation or gamma irradiation, it delivers a clean, physiologically balanced supplement for primary cell expansion and sensitive assay applications.
What is the difference between heat inactivated and gamma irradiated Human Serum?
Heat inactivation (56 °C, 30 min) destroys complement proteins, reducing non-specific activation in immunological assays. Gamma irradiation provides additional inactivation of viruses and mycoplasma while largely preserving growth factors and proteins. The choice depends on your application: heat inactivation is standard for most cell culture work, while gamma irradiation is preferred for higher biosafety requirements or GMP-adjacent processes.
Is Human Serum Type AB available in GMP-compatible quality?
SeamlessBio supplies Human Serum sourced from ISO 9001 and ISO 13485 certified partner facilities, with full batch documentation including CoA, Certificate of Origin, and BSE/TSE statements. For GMP-regulated processes, we offer batch reservation up to 36 months and can provide additional regulatory documents on request. Contact us to discuss your specific compliance requirements.
Can I reserve a specific batch of Human Serum for long-term studies?
Yes — batch reservation is available for up to 36 months. This ensures lot-to-lot consistency for longitudinal studies, regulatory submissions, or manufacturing processes that require a validated, fixed serum lot. Contact our team with your required volume and timeline and we will reserve the validated batch for your programme.
What documentation is included with Human Serum Type AB from SeamlessBio?
Every order ships with a Certificate of Analysis (CoA). Additional documentation — including BSE/TSE statement, Certificate of Origin (COO), sterility certificate, and MSDS — is available on request. All materials are sourced from certified donor centers and processed under traceable, documented conditions.
Request a Quote or Sample
48h response · EU & Swiss Supply · Batch reservation available · Full documentation





