Resources

Comparison guides written for the decisions our customers actually face — which serum variant, which assay format, which detection method. Plus the datasheets and certificates you need before you can raise a purchase order.

Human Serum FBS & Alternatives DMPK & Transporter Assays Bioprocessing Documents & Quality

Human Serum

Five decisions determine which variant fits your process. These guides work through each one.

Human Serum Selection Guide The complete decision path: off-the-clot, blood group, donor gender, heat inactivation, documentation. Start here. Overview Off-the-Clot vs. Plasma-Derived Why the collection method changes the growth factor profile — and how to tell which one you are currently buying. Technical Donor Selection: Type AB, Male, Pooled Isoagglutinins, hCG and the trade-off between lot consistency and donor traceability. Technical Heat Inactivation of Serum What 56 °C for 30 minutes actually does — and the one-passage test that settles it for your cells. Lab practice Switching Human Serum Supplier How to change supplier without losing a validation. Qualification, not purchasing. Process

FBS & Serum Alternatives

Fetal bovine serum, human alternatives and the route to serum-free.

FBS Origin Comparison US, South American, New Zealand and Australian origin — what differs and where it matters for regulatory filings. Sourcing FBS vs. Human Serum When the species barrier matters and when bovine serum remains the pragmatic choice. Comparison Human Serum vs. hPL vs. FBS Which supplement for MSC and ATMP — including the heparin problem behind most xeno-free claims. Comparison HSA vs. rHSA Plasma-derived and recombinant human serum albumin compared across grades and applications. Comparison Serum-Free Cell Culture Adaptation The stepwise route out of serum, and what to expect during the transition. Process

DMPK & Transporter Assays

Assay format, expression system and detection method — the three choices that determine whether your data holds up in review.

HEK293 vs. Sf9 Vesicles How the expression system affects glycosylation, membrane composition and transport kinetics. Technical Vesicle Assay vs. ATPase Assay Outcome versus engine — and the false negatives each format produces. Comparison Vesicle vs. Cell-Based Assay Why passive permeability, not throughput, decides the format for substrate assessment. Comparison Detection Methods Compared Radiolabel, LC-MS/MS or fluorescence — infrastructure, throughput and regulatory standing. Comparison BSEP Inhibition & DILI Why a single BSEP IC50 underestimates hepatotoxicity risk, and what the dual liability concept adds. Safety ciPTEC — Renal Transporters OAT1, OAT3 and OCT2 under ICH M12 — why renal uptake needs cells rather than vesicles. Technical Sf9 vs. HEK293 Vesicle Kits Compared A direct comparison for laboratories evaluating a second source for vesicle kits. Comparison

Bioprocessing

Single-use formats and how to choose between them.

2D vs. 3D Bioprocess Bags Volume range, handling and mixing behaviour — a selection guide for single-use bags. Selection

Documents & Quality

What purchasing and QA ask for before an order goes through.

Datasheets & CoA Specifications and certificates of analysis, available for download. Download Quality Certificates Certifications and quality documentation for our supply chain. Documentation Quality Documents Further documentation on processing, testing and traceability. Documentation Batch Reservation Hold a qualified lot for a running programme instead of re-validating mid-project. Service FAQ Recurring questions on ordering, shipping, documentation and lead times. Support Blog Newer articles and technical notes that have not yet become guides. Articles

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