Ressourcen

Comparison guides written for the decisions our customers actually face — which serum variant, which assay format, which detection method. Plus the datasheets and certificates you need before you can raise a purchase order.

Menschliches Serum FBS & Alternatives DMPK & Transporter Assays Bioprozesstechnik Documents & Quality

Menschliches Serum

Five decisions determine which variant fits your process. These guides work through each one.

Leitfaden zur Auswahl von Humanserum The complete decision path: off-the-clot, blood group, donor gender, heat inactivation, documentation. Start here. Overview „Off-the-Clot“ vs. aus Plasma gewonnen Why the collection method changes the growth factor profile — and how to tell which one you are currently buying. Technical Spenderauswahl: Blutgruppe AB, männlich, gemischt Isoagglutinins, hCG and the trade-off between lot consistency and donor traceability. Technical Hitzeinaktivierung von Serum What 56 °C for 30 minutes actually does — and the one-passage test that settles it for your cells. Lab practice Wechsel des Lieferanten für Humanserum How to change supplier without losing a validation. Qualification, not purchasing. Process

FBS & Serum Alternatives

Fetal bovine serum, human alternatives and the route to serum-free.

FBS – Herkunftsvergleich US, South American, New Zealand and Australian origin — what differs and where it matters for regulatory filings. Sourcing FBS im Vergleich zu Humanserum When the species barrier matters and when bovine serum remains the pragmatic choice. Vergleich Humanes Serum vs. hPL vs. FBS Which supplement for MSC and ATMP — including the heparin problem behind most xeno-free claims. Vergleich HSA vs. rHSA Plasma-derived and recombinant human serum albumin compared across grades and applications. Vergleich Serum-Free Cell Culture Adaptation The stepwise route out of serum, and what to expect during the transition. Process

DMPK & Transporter Assays

Assay format, expression system and detection method — the three choices that determine whether your data holds up in review.

HEK293 vs. Sf9 Vesicles How the expression system affects glycosylation, membrane composition and transport kinetics. Technical Vesikel-Assay vs. ATPase-Assay Outcome versus engine — and the false negatives each format produces. Vergleich Vesicle vs. Cell-Based Assay Why passive permeability, not throughput, decides the format for substrate assessment. Vergleich Detection Methods Compared Radiolabel, LC-MS/MS or fluorescence — infrastructure, throughput and regulatory standing. Vergleich BSEP-Hemmung und DILI Why a single BSEP IC50 underestimates hepatotoxicity risk, and what the dual liability concept adds. Safety ciPTEC — Renal Transporters OAT1, OAT3 and OCT2 under ICH M12 — why renal uptake needs cells rather than vesicles. Technical SOLVO im Vergleich zu Alternativen A direct comparison for laboratories evaluating a second source for vesicle kits. Vergleich

Bioprozesstechnik

Single-use formats and how to choose between them.

2D vs. 3D Bioprocess Bags Volume range, handling and mixing behaviour — a selection guide for single-use bags. Selection

Documents & Quality

What purchasing and QA ask for before an order goes through.

Datasheets & CoA Specifications and certificates of analysis, available for download. Download Quality Certificates Certifications and quality documentation for our supply chain. Dokumentation Quality Documents Further documentation on processing, testing and traceability. Dokumentation Sammelreservierung Hold a qualified lot for a running programme instead of re-validating mid-project. Service Häufig gestellte Fragen Recurring questions on ordering, shipping, documentation and lead times. Support Blog Newer articles and technical notes that have not yet become guides. Articles

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