Archives

What is USP Class VI?

USP Class VI is a biocompatibility standard for plastics used in pharmaceutical and bioprocessing applications. Learn what it means and why it matters for single-use bags.

What is CIPTEC?

CIPTEC is a specialist drug transporter assay service for ABC and SLC transporter characterization. Learn about the assays offered and how to access them.

What is MRP2 (ABCC2)?

MRP2 (ABCC2) is an ABC transporter involved in biliary drug excretion and DDI risk. Learn its function, substrates, inhibitors, and how to assess it in vitro.

What is a Drug-Drug Interaction (DDI)?

DDIs occur when two drugs affect each other’s pharmacokinetics. Learn how transporter-mediated DDIs are assessed and why they matter for regulatory submissions.

What is ADME?

ADME describes the four stages of drug processing in the body. Learn what ADME means, why it matters in drug development, and how transporter assays support ADME studies.

What is an ATPase Assay for ABC Transporters?

The ATPase assay measures ATP hydrolysis by ABC transporters to identify drug substrates and inhibitors. Learn the method, its uses, and when to choose it over vesicle assays.

What is a Vesicular Transport Assay?

The vesicular transport assay uses inside-out membrane vesicles to measure ABC transporter activity. Learn the method, its regulatory context, and how to choose the right kit.

What is an ABC Transporter?

ABC transporters are membrane proteins that transport drugs and metabolites across cell membranes. Learn their role in DMPK, DDI studies, and drug development.

What is Human Platelet Lysate (HPL)?

Human platelet lysate (HPL) is a serum-free, xeno-free FBS alternative for MSC expansion and cell therapy. Learn about GMP-grade HPL and its advantages.

What is BSA (Bovine Serum Albumin)?

BSA (bovine serum albumin) is a versatile protein used in cell culture, diagnostics, and biochemical assays. Learn about grades, purity levels, and applications.