MSC-EVs ohne Serumverunreinigung: Das Medium ist der Ausgangspunkt
Home/ Blog/ MSC Medium for Exosome & EV Production Exosomes · Extracellular Vesicles FBS contains 1010–1012 EVs per mL. Every EV prep from serum-containing culture is co-isolated with bovine vesicles. If your downstream application requires MSC-specific EVs, the medium choice is not optional. Buy serum-free cell culture media from EU stock Request a quote or […]
Sie untersuchen die Immunsuppression durch MSCs? Ihr Serum verfälscht Ihre Ergebnisse
Home/ Blog/ MSC Medium for Immunomodulation Research Immunomodulation · Secretome Research Serum contains cytokines, growth factors and immunoactive proteins at undefined concentrations. If you are measuring IDO, PGE2 or TSG-6 from MSCs expanded in serum, you are measuring a mixture — not your cells. Buy serum-free cell culture media from EU stock Request a quote […]
Single-Use-Bioprocessing-Beutel – GMP-konform, ohne MOQ, Lieferung in der EU
SeamlessBio · Bioprocessing & Single-Use · EU Supplier Single-Use Bioprocessing Bags — GMP-Compliant, No Minimum Order, EU Delivery Your production run is in three weeks. Supplier A from the US: 6–12 weeks lead time. Supplier B from Sweden: minimum one pallet. Supplier C from the US: request a quote first, 5 business days. SeamlessBio supplies […]
Serumfreie Medien für die ATMP-Herstellung: CHO und HEK293 im Vergleich
Serum-Free Media for ATMP Manufacturing: CHO and HEK293 Side by Side | SeamlessBio Advanced therapy medicinal products — gene therapies, cell therapies, tissue-engineered products — depend on upstream cell culture processes that are robust, GMP-compliant and scalable. At the centre of most ATMP upstream processes is one of two production platforms: CHO cells for therapeutic […]
HEK293T vs. HEK293F vs. HEK293FT: Welches serumfreie Medium braucht welche Zelllinie?
HEK293T vs. HEK293F vs. HEK293FT: Which Serum-Free Medium for Each? | SeamlessBio HEK293 is not one cell line. It is a family — and each member has distinct characteristics that affect medium selection. Using a formulation optimised for one sub-line on another is one of the most common sources of suboptimal titre in viral vector […]
Chemisch definiertes vs. proteinfreies CHO-Medium: Warum der Unterschied für GMP wichtig ist
Chemically Defined vs. Protein-Free CHO Medium: What GMP Manufacturers Need to Know | SeamlessBio The terms are often used interchangeably. They should not be. For manufacturers of therapeutic proteins in CHO cells, confusing chemically defined with protein-free can create serious problems at process validation — and occasionally in regulatory submissions. Buy serum-free cell culture media […]
Serumfreies HEK293-Medium: AAV-Produktion vs. lentivirale Vektoren – was ist anders?
Serum-Free HEK293 Medium: AAV vs. Lentiviral Vector Production | SeamlessBio HEK293 cells are the workhorse of viral vector manufacturing. Whether you are producing AAV for gene therapy or lentiviral vectors for CAR-T cell transduction, the chances are HEK293 or one of its derivatives is your production cell line. Buy serum-free cell culture media from EU […]
Warum auf serumfreies CHO-Medium für die mAb-Produktion umsteigen?
Fetal bovine serum has been the default supplement in CHO cell culture for decades. It works — but in 2026, “it works” is no longer good enough for manufacturers of monoclonal antibodies, biosimilars and recombinant proteins. Regulatory pressure, batch variability and the cost of lot reservation are forcing a rethink. Buy serum-free cell culture media […]
Humanes Thrombozytenlysat (hPL): Der Praxisleitfaden für MSC-Expansion und Zelltherapie-Herstellung
Home/ Blog/ Human Platelet Lysate (hPL) Cell Culture · Cell Therapy · MSC · xeno-free Human Platelet Lysate (hPL): The Complete Practitioner’s Guide for MSC Expansion and Cell Therapy Manufacturing SeamlessBio · October 2026 · 9 min read hPL has become the de facto standard for clinical MSC manufacturing — but the switch from FBS […]
CPD- vs. Citratplasma
Blog · Human Plasma · IVD · October 2026 · 5 min read CPD Plasma vs. Citrate Plasma: Key Differences Explained CPD and citrate plasma are both anticoagulated with citrate — but they are not the same matrix. The additional components in CPD solution introduce measurable differences in plasma composition that matter for IVD validation, […]
