CIPTEC (Centre for Innovative Pharmacological and Toxicological Evaluation of Chemicals) is a specialist service offering in vitro drug transporter assays for pharmaceutical companies and CROs. It focuses on ABC transporter characterization — including P-gp, BCRP, BSEP, MRP1–4 — using validated vesicle-based and cell-based methods aligned with FDA, EMA, and ICH M12 guidelines.
Assays Available Through CIPTEC
CIPTEC provides vesicle transport assays (inside-out membrane vesicles), ATPase assays, and transcellular permeability assays across a panel of clinically relevant transporters. These assays generate regulatory-grade data suitable for IND and NDA submissions.
Why Use a Specialist Transporter Assay Service?
Setting up and validating transporter assays in-house requires significant infrastructure, reference materials, and expertise. A specialist provider offers validated assay systems, experienced scientists, and faster turnaround — reducing cost and risk for drug development programs.
SeamlessBio and CIPTEC
SeamlessBio distributes CIPTEC drug transporter assay kits, enabling laboratories to perform these assays in-house with validated, ready-to-use reagents. Contact us to discuss which assay format fits your DMPK program.
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