Chemically Defined CHO Cell Culture Media
GMP-grade, animal-component-free CHO media for biopharmaceutical production — distributed in partnership with CelluPro (ISO 13485, EXCiPACT™). Up to 250 kg GMP powder per batch and 200 L individually filled GMP liquid per run. EU supply, no minimum order.
Chemically Defined
No serum, no hydrolysates — fully defined composition with lot-to-lot reproducibility and no adventitious agent risk.
GMP-Grade Supply
ISO 13485, EXCiPACT™. Up to 250 kg GMP powder per batch, 200 L GMP liquid individually filled per run.
All Major CHO Platforms
CHO-K1, CHO-DG44, CHO-S, CHOZN® — basal, feed and perfusion media for fed-batch and continuous processes.
Custom Development
Cell line-specific media design via CellFit™ platform — HPLC/LC-MS/GC-MS profiling, DoE optimisation, 50+ customised projects completed, avg. yield improvement >50%.
Designed For: Protein CDMOs & Viral Vector Manufacturers
SeamlessBio supplies chemically defined CHO media to two primary customer groups: protein-manufacturing CDMOs running mAb, bispecific, Fc-fusion and recombinant protein production on CHO platforms, and viral vector manufacturers running CHO-based upstream processes for AAV, lentiviral and adenoviral vector supply.
For ATMP-classified products and biologics under EMA/FDA oversight, chemically defined, animal-free raw materials with ISO 13485-certified supply are the expected standard. CelluPro's products are manufactured to that standard from day one, with full batch documentation to support supplier qualification and GMP audit requirements.
Batch reservation for production campaigns is available. Contact SeamlessBio for pricing, lead times and custom lot sizes.
Typische Anwendungsbereiche
- Herstellung monoklonaler Antikörper (mAb)
- Bispecific antibody and Fc-fusion proteins
- Recombinant enzyme and protein production
- Viral vector upstream processes (CHO-based)
- Fed-batch platform development (DG44, GS, CHO-S)
- High-density perfusion manufacturing
- Clinical-grade and commercial CDMO supply
- Cell line development and screening
CelliMax® & DurePro® by CelluPro
All products are chemically defined, animal-component-free and available in GMP powder and liquid formats with full batch documentation.
Basal Media — CelliMax® CHO Series
Serum-free, chemically defined basal media for CHO-K1, CHO-DG44, CHO-S, CHOZN® and CHOSOURCE™ platforms. All GMP Grade.
| Produkt | Cat. No. | Compatible Cell Lines | Format | Zertifizierung |
|---|---|---|---|---|
| CelliMax® CHO E Medium | CPDP037 | CHO-K1, CHO-DG44, CHO-S, CHO-DXB11 | 10 L · 100 L · 500 L | GMP · ISO 13485 |
| CelliMax® CHO E plus Medium | CPDP066 | CHO-K1, CHO-DG44, CHO-S, CHO-DXB11, CHOZN® | 10 L · 100 L · 500 L | GMP · ISO 13485 |
| CelliMax® CHO M Medium | CPDP046 | CHO-K1, CHOK1SV GS-KO®, CHOSOURCE™ CHO-K1, CHO-S | 10 L · 100 L · 500 L | GMP · ISO 13485 |
| CelliMax® MetaCHO Medium | CPDP050 | CHO-K1, CHOK1SV GS-KO®, CHOSOURCE™ CHO-K1, CHO-DG44, CHO-DXB11 | 10 L · 100 L · 500 L | GMP · ISO 13485 |
| CelliMax® Zeta02 plus Medium | CPDP089 | CHOZN®, CHO-K1 | 10 L · 100 L · 500 L | GMP · ISO 13485 |
| CelliMax® Versa Medium (Universal) | CPDP098 | CHO-K1, CHOZN®, CHO-DG44, CHO-S, CHO-DXB11, CHOK1SV GS-KO®, CHOSOURCE™ CHO-K1 — also validated for HEK293 | 10 L · 100 L · 500 L | GMP · ISO 13485 |
Feed Media
| Produkt | Cat. No. | Type | Compatible Cell Lines | Sizes | Zertifizierung |
|---|---|---|---|---|---|
| CelliMax® CHO FGa Medium | CPDP062 | Feed Medium A | CHO-K1, CHOK1SV GS-KO®, CHOSOURCE™ CHO-K1, CHO-DG44, CHO-DXB11 | 1 L · 5 L · 20 L · 100 L | GMP · ISO 13485 |
| CelliMax® CHO FGa plus Medium | CPDP067 | Feed Medium A | CHOZN®, CHO-K1, CHOSOURCE™ CHO-K1, CHO-DG44, CHO-DXB11 | 1 L · 5 L · 20 L · 100 L | GMP · ISO 13485 |
| CelliMax® CHO FGb Medium | CPDP064 | Feed Medium B | CHOZN®, CHO-K1, CHOK1SV GS-KO®, CHOSOURCE™ CHO-K1, CHO-DG44, CHO-DXB11 | 1 L · 10 L | GMP · ISO 13485 |
Perfusion Media — DurePro® Series
Ready-to-use, nutrient-enriched perfusion media for N-stage continuous manufacturing. Cumulative protein yield up to 80 g/L within 30 days. Liquid stability >45 days at ambient temperature.
| Produkt | Cat. No. | Format | Sizes | Lagerung | Zertifizierung |
|---|---|---|---|---|---|
| DurePro® HD Perfusion Medium | CPDP082 | Powder (GMP Grade) | 5 L · 50 L · 500 L | 2–8 °C | GMP · ISO 13485 |
| DurePro® EZ Perfusion Medium | CPDP084 | Powder (GMP Grade) | 5 L · 50 L · 500 L | 2–8 °C | GMP · ISO 13485 |
GMP Batch Capacities
CellFit™ — Customized Media Development Platform
CelluPro offers tailored media formulation services for organisations requiring solutions designed for specific cell lines, process requirements or expression systems. 50+ customised development projects completed · 20+ media replacement projects · avg. yield improvement >50%.
Metabolic Profiling
Cell line-specific metabolic analysis using HPLC, LC-MS, GC-MS and ICP to identify limiting nutrients and accumulating metabolites.
DoE Optimisation
Component screening and titration across carbon sources, amino acid ratios, trace elements and growth factors using Design of Experiments methodology.
Scale-Up Validation
Translation from shake flask to bioreactor — fed-batch or perfusion — with titre and product quality benchmarking.
IP Transfer
Full IP transfer to client, co-ownership or licensed formulation. GMP documentation and batch records included.
CelluPro — ISO 13485 · EXCiPACT™
SeamlessBio distributes CelluPro's CelliMax® and DurePro® product lines in the EU and UK. Founded in 2018, CelluPro operates cGMP-compliant powder manufacturing with world-leading pin mill technology and a fully integrated MES system. Over 700 GMP production batches completed with a >98% quality pass rate. 75+ pipelines supported worldwide.
ISO 13485 · ISO 9001 · EXCiPACT™ accreditation · EU, FDA and NMPA compliant. GMP powder up to 250 kg/batch · GMP liquid up to 200 L/run, individually filled.
EU supply chain active. EU-based warehousing in Germany in planning — contact SeamlessBio for current lead times.
Request a sample or quote for CHO cell culture media
Free test samples available. No minimum order. 48-hour quote turnaround. Contact us for batch documentation, technical datasheets and custom lot sizes.
KontaktHäufig gestellte Fragen
What CHO cell lines are compatible with CelliMax® media?
The CelliMax® portfolio covers CHO-K1, CHO-DG44, CHO-S, CHO-DXB11, CHOZN®, CHOK1SV GS-KO® and CHOSOURCE™ CHO-K1. CelliMax® CHO M and MetaCHO are optimised for GS-based systems; CelliMax® CHO E / E plus for DHFR-based platforms; CelliMax® Zeta02 plus specifically for CHOZN®; CelliMax® Versa supports all major CHO subtypes and is additionally validated for HEK293. Contact SeamlessBio to confirm compatibility with your specific cell line.
Are these media suitable for GMP manufacturing and clinical supply?
Yes. CelliMax® and DurePro® are manufactured under ISO 13485-certified QMS with EXCiPACT™ accreditation, compliant with EU GMP guidelines, FDA requirements and ICH Q11 expectations for chemically defined raw materials. Full batch documentation supports supplier qualification and GMP audit requirements.
What GMP batch sizes are available?
GMP powder is available in batches up to 250 kg. GMP liquid media are available in individually filled batches up to 200 L per run. Both formats are supplied with full batch documentation (CoA, SDS, traceability records). Contact SeamlessBio for campaign supply and batch reservation.
Is there a minimum order quantity?
No minimum order quantity. Free test samples are available for product evaluation. Volume pricing and batch reservation available on request.
Can CelluPro develop a custom media formulation for our cell line?
Yes. CelluPro offers custom media development via the CellFit™ Customized Development Platform — cell line-specific metabolic profiling using HPLC/LC-MS/GC-MS analytics, DoE-based optimisation, scale-up validation and IP transfer options. Over 50 customised development projects and 20+ media replacement projects completed, with an average yield improvement of >50%. Contact SeamlessBio to discuss your process requirements.
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